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Nanosensor Cartridge for Bioagent Detection within Geospatial Networked Motes

Award Information

Department of Defense
Award ID:
Program Year/Program:
2011 / SBIR
Agency Tracking Number:
Solicitation Year:
Solicitation Topic Code:
Solicitation Number:
Small Business Information
UES, Inc.
4401 Dayton-Xenia Road Dayton, OH 45432-1894
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Woman-Owned: Yes
Minority-Owned: No
HUBZone-Owned: No
Phase 2
Fiscal Year: 2011
Title: Nanosensor Cartridge for Bioagent Detection within Geospatial Networked Motes
Agency: DOD
Contract: W9132V-10-C-0001
Award Amount: $1,318,309.00


Detection of biological warfare agents in a real-world setting is an increasingly urgent problem. Many of the current state-of-the-art sensors require large biomolecules, such as antibodies, to achieve binding of the target molecule and subsequent reporting of the binding event. This type of detection is not stable under deployed environmental conditions and often requires blocking and washing steps. These technical hurdles are a drawback when considering use of these technologies in a battlefield situation. Here, we propose a sensor that is based on stable biomolecules that act as ligands for the target(s) of interest. Due to their small size, these ligands are not susceptible to conformational instability and the sensors should have a long lifetime even when deployed. Additionally, the sensor incorporates an exponential amplification of the output signal when the target of interest binds, effectively eliminating the background and false positive results.

Principal Investigator:

Melanie Tomczak
Research Scientist
(937) 426-6900

Business Contact:

Bryce Skinn
Business Relations Manage
(937) 426-6900
Small Business Information at Submission:

UES, Inc.
4401 Dayton-Xenia Road Dayton, OH -

EIN/Tax ID: 310797776
Number of Employees:
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No