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Nanosensor Cartridge for Bioagent Detection within Geospatial Networked Motes

Award Information
Agency: Department of Defense
Branch: Army
Contract: W9132V-10-C-0001
Agency Tracking Number: A2-3928
Amount: $1,318,309.00
Phase: Phase II
Program: SBIR
Solicitation Topic Code: A08-169
Solicitation Number: 2008.3
Timeline
Solicitation Year: 2008
Award Year: 2011
Award Start Date (Proposal Award Date): 2010-01-15
Award End Date (Contract End Date): N/A
Small Business Information
4401 Dayton-Xenia Road
Dayton, OH -
United States
DUNS: 074689217
HUBZone Owned: No
Woman Owned: No
Socially and Economically Disadvantaged: No
Principal Investigator
 Melanie Tomczak
 Research Scientist
 (937) 426-6900
 mtomczak@ues.com
Business Contact
 Bryce Skinn
Title: Business Relations Manage
Phone: (937) 426-6900
Email: bskinn@ues.com
Research Institution
 Stub
Abstract

Detection of biological warfare agents in a real-world setting is an increasingly urgent problem. Many of the current state-of-the-art sensors require large biomolecules, such as antibodies, to achieve binding of the target molecule and subsequent reporting of the binding event. This type of detection is not stable under deployed environmental conditions and often requires blocking and washing steps. These technical hurdles are a drawback when considering use of these technologies in a battlefield situation. Here, we propose a sensor that is based on stable biomolecules that act as ligands for the target(s) of interest. Due to their small size, these ligands are not susceptible to conformational instability and the sensors should have a long lifetime even when deployed. Additionally, the sensor incorporates an exponential amplification of the output signal when the target of interest binds, effectively eliminating the background and false positive results.

* Information listed above is at the time of submission. *

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