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Nanosensor Switches for Detection of Toxins, Pathogens, and Small Molecules

Award Information

Agency:
Department of Defense
Branch:
Air Force
Award ID:
Program Year/Program:
2012 / STTR
Agency Tracking Number:
F11B-T09-0134
Solicitation Year:
2011
Solicitation Topic Code:
AF11-BT09
Solicitation Number:
2011.B
Small Business Information
ORTHOSYSTEMS, INC.
100 Intrepid Lane Suite 1 Syracuse, NY 13205-
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Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
 
Phase 1
Fiscal Year: 2012
Title: Nanosensor Switches for Detection of Toxins, Pathogens, and Small Molecules
Agency / Branch: DOD / USAF
Contract: FA8650-12-M-5123
Award Amount: $99,967.00
 

Abstract:

ABSTRACT: This phase I STTR project is a proof of concept study for developing near real-time, nanoparticle based sensors that detect the presence of specified toxins, pathogens, proteins, metabolites and small molecules. The specificity and sensitivity of this"nanosensor"is imparted by aptamer recognition that is engineered into a novel, patented technology we termed as an Alloswitch. These Alloswitch sensors will be embedded in nanoparticles to create a"nanosensor"that are capable of long term storage, easy to administer to patients, and facilitate entry and uptake by cells. BENEFIT: There is a clear need for detection of bio-terror agents and new options for treatment of affected military and civilian personnel. There are also military and civilian needs for rapid diagnostics in bodily fluids and cells. Our nanosensor platform will enable rapid detection of targeted microorganisms, viruses, proteins, and metabolites, and also provide therapeutic options. Detection can be made in bodily fluids or specifically chosen cell types. Success in these applications will be of tremendous commercial and societal value.

Principal Investigator:

Mark McPike
CSO
(315) 299-7167
mpmcpike@aptamatrix.com

Business Contact:

Mark McPike
CSO
(315) 299-7167
mpmcpike@aptamatrix.com
Small Business Information at Submission:

AptaMatrix
100 Intrepid Lane Suite 1 Syracuse, NY 13205-

EIN/Tax ID: 841618920
DUNS: N/A
Number of Employees:
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
Research Institution Information:
Syracuse University
Biomedical&Chemical Engineer
Syracuse Biomaterials Inst.
Syracuse, NY 13244-3244
Contact: Rebecca Bader
Contact Phone: (315) 443-9709