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Development and Validation of NIRS-Based Sinusitis Screening

Award Information

Agency:
Department of Health and Human Services
Branch:
N/A
Award ID:
Program Year/Program:
2012 / SBIR
Agency Tracking Number:
R44DC012018
Solicitation Year:
2012
Solicitation Topic Code:
NIDCD
Solicitation Number:
PA10-050
Small Business Information
PRAXIS BIOSCIENCES, LLC
11 MCCLINTOCK CT IRVINE, CA -
View profile »
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
 
Phase 2
Fiscal Year: 2012
Title: Development and Validation of NIRS-Based Sinusitis Screening
Agency: HHS
Contract: 4R44DC012018-02
Award Amount: $794,931.00
 

Abstract:

DESCRIPTION (provided by applicant): In the U.S., chronic sinusits is associated with over 40 million visits to physicians and health care providers each year. Sinusitis is diagnosed based on clinical history which is difficult to correctly ascertain, andhence misdiagnosis leads to both over-treatment (i.e. antibiotics) and under-treatment (i.e. misdiagnosis as allergies or migraine). Praxis Biosciences, LLC aims to develop and deliver a very low-cost optical imaging tool for quick and simple assessment ofsinusitis suitable for use by both primary care doctors and physician extenders. In this proposal, we will first improve on the design of a novel validated prototype developed at the Beckman Laser Institute at UC Irvine by optimizing device form factor, robustness, and optical design. Our device is based upon the principles of near-infrared (NIR) trans-illumination but exploits the unique near infrared optical properties of living tissue to generate substantially greater signal yield. In the second phase of the fast-track, we will validate its efficacy of this market-ready optimized device via a clinical study with Ear, Nose and Throat (ENT) specialists and primary care physicians. The proposed low-cost optical imaging tool will be able to provide means tobetter identify patients with acute sinusitis and then monitor the response to therapy in primary care settings. Ultimately, our device will help reduce the health-care costs related by optimizing and streamlining diagnosis and treatment.

Principal Investigator:

Joon You
949-371-6226
praxisbio@gmail.com

Business Contact:

Joon You
949-371-6226
praxisbio@gmail.com
Small Business Information at Submission:

PRAXIS BIOSCIENCES, LLC
11 MCCLINTOCK CT IRVINE, CA -

EIN/Tax ID: 127293713
DUNS: N/A
Number of Employees: N/A
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No