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Company Information:

Company Name:
DETROIT R AND D, INC.
Address:
DETROIT R AND D, INC.
DETROIT, MI 48201-
Phone:
(313) 961-1606
URL:
EIN:
383375464
DUNS:
030673508
Number of Employees:
7
Woman-Owned?:
Yes
Minority-Owned?:
Yes
HUBZone-Owned?:
No

Award Totals:

Program/Phase Award Amount ($) Number of Awards
SBIR Phase I $447,067.00 2
SBIR Phase II $989,975.00 1

Award List:

SBIR TOPIC 294 PHASE I - DEVELOPMENT OF GLYCOSYLATION-SPECIFIC RESEARCH REAGENTS (ANTIBODIES AND APTAMERS)

Award Year / Program / Phase:
2011 / SBIR / Phase I
Award Amount:
$147,520.00
Agency:
HHS
Principal Investigator:
Hyesook Kim – (248) 539-3236
Abstract:
Protein O-GlcNAcylation (N-acetylglucosamine modification), which decreases phosphorylation, plays a critical role in cell-cycle regulation, apoptosis and signal transduction. So far, ~120 O-GlcNAcylated human proteins have been found. To elucidate functions of O-GlcNAcylation, it is necessary to… More

Glycoproteins and Glycan-Binding IgGs: Biomarkers for Cancer and Inflammatory Di

Award Year / Program / Phase:
2012 / SBIR / Phase I
Award Amount:
$299,547.00
Agency:
HHS
Principal Investigator:
Hyesook Kim – 248-539-3236
Abstract:
DESCRIPTION (provided by applicant): Structurally varied glycans displayed unexpectedly strong efects on inflammation and cancer progression. Glycan recognition by glycan-binding proteins is involved with physiological and disease-related cell adhesion orcell signaling. Tumor tissues secrete… More

SBIR PHASE II TOPIC 294:SITE-SPECIFIC ANTIBODIES FOR GLCNACYLATED PROTEINS IN CAN

Award Year / Program / Phase:
2013 / SBIR / Phase II
Award Amount:
$989,975.00
Agency:
HHS
Principal Investigator:
Hyesook Kim – 248-539-3236
Abstract:
O-GlcNAcylation of proteins plays a critical role in cell cycle regulation, apoptosis and signal transduction. Modification of O-GlcNAcylation of proteins by O-GlcNAc transferase is reversible by the activity of O-GlcNAcase. Addition and removal of O-GlcNAc moiety to serine or threonine regulate the… More