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Company Information:

Company Name: DETROIT R AND D, INC.
City: DETROIT
State: MI
Zip+4: 48201-
Woman-Owned: Yes
Minority-Owned: Yes
HUBZone-Owned: No
Phone: (313) 961-1606

Award Totals:

Program/Phase Award Amount ($) Number of Awards
SBIR Phase I $299,547.00 1
SBIR Phase II $989,975.00 1

Award List:

Glycoproteins and Glycan-Binding IgGs: Biomarkers for Cancer and Inflammatory Di

Award Year / Program / Phase: 2012 / SBIR / Phase I
Agency: HHS
Principal Investigator: Hyesook Kim – 248-539-3236
Award Amount: $299,547.00
Abstract:
DESCRIPTION (provided by applicant): Structurally varied glycans displayed unexpectedly strong efects on inflammation and cancer progression. Glycan recognition by glycan-binding proteins is involved with physiological and disease-related cell adhesion orcell signaling. Tumor tissues secrete… More

SBIR PHASE II TOPIC 294:SITE-SPECIFIC ANTIBODIES FOR GLCNACYLATED PROTEINS IN CAN

Award Year / Program / Phase: 2013 / SBIR / Phase II
Agency: HHS
Principal Investigator: Hyesook Kim – 248-539-3236
Award Amount: $989,975.00
Abstract:
O-GlcNAcylation of proteins plays a critical role in cell cycle regulation, apoptosis and signal transduction. Modification of O-GlcNAcylation of proteins by O-GlcNAc transferase is reversible by the activity of O-GlcNAcase. Addition and removal of O-GlcNAc moiety to serine or threonine regulate the… More