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Encapsulation Matrix for Improved Biological Specimen Storage and Recovery

Award Information

Agency:
Department of Defense
Branch:
N/A
Award ID:
Program Year/Program:
2012 / SBIR
Agency Tracking Number:
11SB2-0119
Solicitation Year:
2011
Solicitation Topic Code:
SB112-005
Solicitation Number:
2011.2
Small Business Information
Luna Innovations Incorporated
1 Riverside Circle Suite 400 Roanoke, VA 24016-4962
View profile »
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
 
Phase 1
Fiscal Year: 2012
Title: Encapsulation Matrix for Improved Biological Specimen Storage and Recovery
Agency: DOD
Contract: W31P4Q-12-C-0039
Award Amount: $100,000.00
 

Abstract:

Luna Innovations will establish the feasibility of modifying our novel bio-encapsulation techniques for enhanced preservation of biological samples. The proposed technology has been successfully applied to protein and whole cell encapsulation, providing significant improvements in storage life-time and temperature stability. This unique preservation method has the ability to reduce analyte loss while still maintaining analyte integrity. During Phase I, Luna will develop modified encapsulation matrices for the preservation of two different biological samples (blood and urine). In order to demonstrate enhanced recovery of analytes, various biomarkers (DNA, RNA, and cytokines) will be quantified as a function of preservation time, temperature, and degree of dehydration. Phase II will focus on increasing the storage lifetime of the samples as well as extending the range of suitable storage environments. Concurrently, Luna will be working to adapt this novel bio-encapsulation technique for integration into applications such as therapeutic drug monitoring, newborn screening, biomarker discovery and qualification research.

Principal Investigator:

Blaine Butler
Principal Investigator
(434) 220-2509
butlerb@lunainnovations.com

Business Contact:

Shirley Evans
Sr. Contract Administrator
(540) 961-6724
submissions302@lunainnovations.com
Small Business Information at Submission:

Luna Innovations Incorporated
1 Riverside Circle Suite 400 Roanoke, VA -

EIN/Tax ID: 541560050
DUNS: N/A
Number of Employees:
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No