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A Vacuum-Actuated Microneedle Patch with Integrated Reservoir (VAMPIRE) for…

Award Information

Agency:
Department of Defense
Branch:
N/A
Award ID:
Program Year/Program:
2012 / SBIR
Agency Tracking Number:
D122-003-0054
Solicitation Year:
2012
Solicitation Topic Code:
SB122-003
Solicitation Number:
2012.2
Small Business Information
Lynntech, Inc.
2501 Earl Rudder Freeway South College Station, TX 77845-
View profile »
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
 
Phase 1
Fiscal Year: 2012
Title: A Vacuum-Actuated Microneedle Patch with Integrated Reservoir (VAMPIRE) for Minimally Invasive Blood Sampling
Agency: DOD
Contract: W31P4Q-13-C-0032
Award Amount: $100,000.00
 

Abstract:

Blood comprises a comprehensive compendium of biomolecules that is fully representative of human health; identification of specific biomarkers is useful for diagnosis, prediction, and monitoring of health, in real-time, making it the bio-fluid of choice for analytical applications. However, owing to the broad range of biomolecules in blood (10-log orders), the distribution of very low-level biomarkers in small volumes is governed by Poissonian principles and is not adequately representative. Thus, pinprick-based techniques often are not useful for accurate detection of such biomarkers. It is necessary to collect a larger, more representative volume of blood, but this is non-trivial, often requiring clinically-trained phlebotomists and highly invasive, painful methods. Lynntech is proposing the development of a low power/cost, minimally invasive, and relatively pain-free single-use device (VAMPIRE) for collecting larger blood samples (0.1-1 mL). The proposed device will be developed with a view towards potential future in-line integration with extant point-of-care diagnostics for easy, deployable use in remote settings. Additionally, the integrated reservoir will be designed to facilitate sample collection and storage for later-expanded clinical testing, if necessary. Sample collection is the weakest link in the chain of bioanalysis; VAMPIRE will provide unsurpassed, controlled, reproducible, blood-sample collection abilities that will bridge this niche.

Principal Investigator:

Sriram Shankar
Sr. Scientist
(979) 764-2200
sriram.shankar@lynntech.com

Business Contact:

G. R. Hisaw
Sr. Contracts Administrator
(979) 764-2218
renee.hisaw@lynntech.com
Small Business Information at Submission:

Lynntech, Inc.
2501 Earl Rudder Freeway South College Station, TX -

EIN/Tax ID: 742463014
DUNS: N/A
Number of Employees:
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No