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First Generation of Controlled-Release Bacteriocins/Anti-Microbials

Award Information

Department of Defense
Award ID:
Program Year/Program:
2012 / SBIR
Agency Tracking Number:
Solicitation Year:
Solicitation Topic Code:
Solicitation Number:
Small Business Information
Metna Co.
1926 Turner Street Lansing, MI 48906-4051
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Woman-Owned: Yes
Minority-Owned: No
HUBZone-Owned: No
Phase 1
Fiscal Year: 2012
Title: First Generation of Controlled-Release Bacteriocins/Anti-Microbials
Agency: DOD
Contract: W911QY-12-P-0123
Award Amount: $99,969.00


Food safety has become an increasingly important international concern; it is also a critical issue for the Warfighter who is encountering growing bioterrorism and proliferation of foodborne illnesses. Biopreservation is a technique used to increase shelf life and food safety through natural, biological methods, and could resolve some major food-related issues. Among the wide spectrum of antibacterial products based on microorganisms, the bacteriocins have attracted the greatest attention for food preservation; their use, however, is still limited due to complicated factors, including interaction with the foods, low solubility at high pH, and short shelf life. This project will develop and commercialize a new generation of controlled-release bacteriocins/anti-microbials with nanoencapsulation using biodegradable polymers to advance biopreservation for improving food safety. The project will specifically target effective inhibition of a broad range of spoilage bacteria, pathogens and spores over the extended shelf life of ration components used for military feeding. The following objectives will be achieved in the Phase I effort: i) identification of viable potential bacteriocins/anti-microbials complexes for effective killing of both Gram-negative and Gram-positive foodborne pathogens; ii) development of nanoencapsulated bacteriocins/anti-microbials, and thorough assessment of their antimicrobial activity; and iii) modeling the in-vitro release of nanoencapsulated bacterocins/anti-microbials.

Principal Investigator:

Jue Lu
Director of Product Development
(517) 485-1402

Business Contact:

Parviz Soroushian
(517) 485-9583
Small Business Information at Submission:

Metna Co.
1926 Turner Street Lansing, MI -

EIN/Tax ID: 452366079
Number of Employees:
Woman-Owned: Yes
Minority-Owned: No
HUBZone-Owned: No