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Company Information:

Company Name: SPHYNKX THERAPEUTICS, LLC
City: CHARLOTTESVILLE
State: VA
Zip+4: 22901-3001
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
Website URL: N/A
Phone: N/A

Award Totals:

Program/Phase Award Amount ($) Number of Awards
SBIR Phase I $469,659.00 2

Award List:

Improving in vivo stability of sphingosine kinase inhibitors

Award Year / Program / Phase: 2012 / SBIR / Phase I
Agency: HHS
Principal Investigator: Steven B. Thorpe – 434-906-0275
Award Amount: $152,792.00
Abstract:
DESCRIPTION (provided by applicant): We and others have hypothesized that inhibiting SphK1 is a powerful therapeutic strategy in pathologies that are characterized by cell hyperproliferation, e.g. cancer and fibrosis. This hypothesis was generated largelythrough the use interfering RNA strategies -… More

Phase II Commercialization of Continuous Countercurrent Tangential Chromatography

Award Year / Program / Phase: 2013 / SBIR / Phase I
Agency: HHS
Principal Investigator: Steven B. Thorpe – 703-850-7206
Award Amount: $316,867.00
Abstract:
DESCRIPTION: Vascular leak is a hallmark of tissue injury, and results in the movement of plasma into the interstitium where immune mediators and clotting factors invade the injured tissue. Left to persist, vascular leak can exacerbate inflammation and lead to a chronic and abnormal wound healing… More