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A low-cost instrument for nucleic acid isolation.

Award Information

Agency:
Department of Health and Human Services
Branch:
N/A
Award ID:
Program Year/Program:
2012 / SBIR
Agency Tracking Number:
R43GM103053
Solicitation Year:
2012
Solicitation Topic Code:
NIGMS
Solicitation Number:
PA11-096
Small Business Information
AKONNI BIOSYSTEMS, INC.
400 Sagner Avenue Suite 300 FREDERICK, MD 21701-6082
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Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
 
Phase 1
Fiscal Year: 2012
Title: A low-cost instrument for nucleic acid isolation.
Agency: HHS
Contract: 1R43GM103053-01
Award Amount: $280,784.00
 

Abstract:

DESCRIPTION (provided by applicant): Sample preparation frequently presents a bottleneck for clinical molecular biology workflows. Whereas there are many readout detection modalities, there are only a handful of automated sample preparation workflow strategies. Existing instruments that are built around these sample preparation strategies and chemistries range in cost from 17- 150k, and yet they still do not include an integrated method of lysing difficult-to-disrupt organisms such as gram-positive bacteria or the acid fast bacilli (i.e., Mycobacterium). To address these limitations, we propose to integrate Akonni's sample preparation technologies into a low-cost automated instrument that can process a variety of sample types such as blood, nasopharyngeal swabs, and nasopharyngeal aspirate with a simple-to-use consumable kit. PUBLIC HEALTH RELEVANCE: Molecular diagnostics, which are tests that analyze the DNA and/or RNA in a sample, are becoming increasingly prevalent among clinical laboratory testmethods. An important, yet challenging, procedure, required of these tests, is to remove the DNA/RNA from the sample and wash away the impurities. We seek to develop a low-cost automated instrument to address this challenge

Principal Investigator:

Christopher G. Cooney
301-698-0101
cooney@akonni.com

Business Contact:

Christopher G. Cooney
301-698-0101
cooney@akonni.com
Small Business Information at Submission:

AKONNI BIOSYSTEMS, INC.
400 Sagner Avenue Suite 300 FREDERICK, MD 21701-6082

EIN/Tax ID: 116166492
DUNS: N/A
Number of Employees: N/A
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No