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OTHER FUNCTIONS - RECOMBINANT ANTIBODIES AS AFFINITY CAPTURES

Award Information

Agency:
Department of Health and Human Services
Branch:
N/A
Award ID:
Program Year/Program:
2012 / SBIR
Agency Tracking Number:
N44HV120047
Solicitation Year:
2012
Solicitation Topic Code:
NHLBI
Solicitation Number:
Small Business Information
AVANTGEN, INC.
AVANTGEN, INC. 10151 Pacific Mesa Blvd. SAN DIEGO, CA 92129-4571
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Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
 
Phase 2
Fiscal Year: 2012
Title: OTHER FUNCTIONS - RECOMBINANT ANTIBODIES AS AFFINITY CAPTURES
Agency: HHS
Contract: N44HV120047
Award Amount: $990,779.00
 

Abstract:

One of the biggest roadblocks to the translation of basic proteomic discoveries to potential clinical applications is the lack of robust and sensitive reagents that can capture a given protein reproducibly from different types of matrixes. While antibodieshave been the major players of protein capture, alternate reagents are urgently needed to overcome the lack of sensitivity, specificity, and reproducibility associated with many of the current antibodies to help translate cardiovascular protein biomarkerdiscoveries into clinical utility. Development of sensitive, well characterized, reproducible and cost effective reagents that can capture proteins involved in cardiovascular physiology or pathology would greatly benefit the cardiovascular research community. The goal of this contract is to generate high affinity antibodies against a panel of cardiovascular markers using a proprietary yeast display antibody library system.

Principal Investigator:

Xiaomin Fan
858-768-8107
XFAN@AVANTGEN.COM

Business Contact:

Xiaomin Fan
858-768-8107
XFAN@AVANTGEN.COM
Small Business Information at Submission:

AVANTGEN, INC.
AVANTGEN, INC. SAN DIEGO, CA 92129-4571

EIN/Tax ID: 120215784
DUNS: N/A
Number of Employees: N/A
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No