USA flag logo/image

An Official Website of the United States Government

Developing a Point-of-Care Diagnostic Assay for Leptospirosis

Award Information

Department of Defense
Award ID:
Program Year/Program:
2010 / SBIR
Agency Tracking Number:
Solicitation Year:
Solicitation Topic Code:
Army 09-105
Solicitation Number:
Small Business Information
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
Phase 1
Fiscal Year: 2010
Title: Developing a Point-of-Care Diagnostic Assay for Leptospirosis
Agency / Branch: DOD / ARMY
Contract: W81XWH-10-C-0017
Award Amount: $118,443.00


The objective of this study is to develop a robust, field deployable, and a cost effective rapid screening assay for the detection of Leptospirosis infection caused by Leptospira pathogens using human blood and sera. The test will utilize a lateral flow based immunochromatographic system (dipstick). The proposed assay would be very useful screening tool to assess leptospirosis infection in the fields, in remote areas, and on how complexity situation. Such a test would facilitate diagnosis and treatment for military personnel presenting febrile illness. A rapid assay would also help in Leptospirosis eradication programs. In this Phase I study we will develop/acquire antibody and antigen reagents for use in development of prototype Leptospirosis detection assays. We will then construct prototype assay that will be evaluated using archived samples from infected individuals. Further development of the assay would take place in a phase II proposal

Principal Investigator:

Stan Morkowski

Business Contact:

Estela Raychaudhuri
Senior Scientist
Small Business Information at Submission:

InBios International
562 1st Ave S, Suite 600 Seattle, WA 98104

EIN/Tax ID: 911791824
Number of Employees:
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No