USA flag logo/image

An Official Website of the United States Government

Replicon Particle Vaccine for White Spot Syndrome Virus in Marine Shrimp

Award Information

Agency:
Department of Agriculture
Branch:
N/A
Award ID:
99210
Program Year/Program:
2010 / SBIR
Agency Tracking Number:
2010-00150
Solicitation Year:
N/A
Solicitation Topic Code:
8.7
Solicitation Number:
N/A
Small Business Information
Harrisvaccines Inc.
1102 SOUTHERN HILLS DR STE 101 Ames, IA 50010-8222
View profile »
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
 
Phase 1
Fiscal Year: 2010
Title: Replicon Particle Vaccine for White Spot Syndrome Virus in Marine Shrimp
Agency: USDA
Contract: N/A
Award Amount: $79,700.00
 

Abstract:

WSSV is the most serious disease in farmed marine shrimp causing considerable financial losses throughout the last decade across the globe. It infects a wide variety of crustacean hosts including numerous species of wild and cultured marine shrimp, crayfish, and prawns. Although a multitude of vaccination strategies have been attempted with mixed results, no viable commercial product exists on the market. Our preliminary data demonstrate that Alphavirus replicon particles (RP) and a Sindbis (SIN) virus vector infect and express green fluorescent protein in shrimp following injection. Evidence also exists in other invertebrates that oral exposure through immersion has been a successful challenge model with other Alphaviruses. It is proposed that utilizing alphaviruses or alphavirus replicon particles would provide an effective platform for gene expression for mass WSSV vaccination of farmed shrimp.

Principal Investigator:

Kurt I. Kamrud
null
9199091726
kurt.sirrah@gmail.com

Business Contact:

Kurt Kamrud
null
9199091726
kurt.sirrah@gmail.com
Small Business Information at Submission:

HARRISVACCINES, INC.
2325 N LOOP DR Ames, IA 50010

EIN/Tax ID: 262097340
DUNS: N/A
Number of Employees:
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No