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Programmable transdermal drug delivery

Award Information

Agency:
Department of Health and Human Services
Branch:
N/A
Award ID:
88822
Program Year/Program:
2010 / SBIR
Agency Tracking Number:
AR055837
Solicitation Year:
N/A
Solicitation Topic Code:
NIAMS
Solicitation Number:
N/A
Small Business Information
LOS GATOS RESEARCH
67 E EVELYN AVE STE3 Mountain View, CA 94041-1529
View profile »
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
 
Phase 2
Fiscal Year: 2010
Title: Programmable transdermal drug delivery
Agency: HHS
Contract: 2R44AR055837-02
Award Amount: $748,768.00
 

Abstract:

DESCRIPTION (provided by applicant): Prostate cancer and central precocious puberty - linked through improper gonadal steroid levels - are most common in either the elderly or youth populations. Similar gonadal steroid problems also connected to endometrio sis. Some traditional methodologies for treating these illnesses involves daily injections of medicine, which can become painful or be forgotten, result in under-dosing. Los Gatos Research is developing an alternative method for delivering time-controlled drug formulations that is practically pain free. Furthermore, the novel technology provides an extended, programmable release platform that helps patients avoid the need to remember to take medication (particularly important for portions of the elderly pop ulation) and offers the potential to use less medicine to produce the same effect due to the ability to customize the delivery to the individual patient. The technologies developed in this proposed project enable programmable, microfluidic transdermal patc hes to provide a means for delivering large molecular weight drug formulations that is controlled, painless, and direct. The specific aims of the Phase II project include upgrading the unique programmable transdermal patches, testing and validating their p erformance capabilities, optimizing them for rapid, controlled delivery of medication to control gonadal steroid levels, and conducting initial pre- clinical trials of the patches.

Principal Investigator:

Micah Yairi
6509657841
M.YAIRI@LGRINC.COM

Business Contact:

Micah Yairi
d.baer@lgrinc.com
Small Business Information at Submission:

LOS GATOS RESEARCH
LOS GATOS RESEARCH 67 E EVELYN AVE, STE 3 MOUNTAIN VIEW, CA -

EIN/Tax ID: 177035868
DUNS: N/A
Number of Employees: N/A
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No