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Early detection of Alzheimer's (MCI stage): Analysis of plasma cell-free miRNA

Award Information

Agency:
Department of Health and Human Services
Branch:
N/A
Award ID:
Program Year/Program:
2013 / SBIR
Agency Tracking Number:
R43MH100712
Solicitation Year:
2013
Solicitation Topic Code:
NIMH
Solicitation Number:
PA11-133
Small Business Information
CENTER FOR SOCIAL INNOVATION, LLC
200 Reservoir Street Needham, MA 02494-
View profile »
Woman-Owned: Yes
Minority-Owned: No
HUBZone-Owned: No
 
Phase 1
Fiscal Year: 2013
Title: Early detection of Alzheimer's (MCI stage): Analysis of plasma cell-free miRNA
Agency: HHS
Contract: 1R43MH100712-01
Award Amount: $596,463.00
 

Abstract:

DESCRIPTION (provided by applicant): Service disengagement is one of the most pervasive and challenging problems currently facing America's mental health system. People in recovery have attributed their disengagement from care to having poor alliances withcare providers, including experiences of not being offered the opportunity to make decisions and collaborate in their own treatment. In response, the mental health system is moving toward wider use of Person-Centered Care Planning (PCCP), an evidence-based intervention designed to maximize consumer choice and ownership of the treatment process. While PCCP has been embraced by many, the model has not been widely disseminated, and many people with mental illnesses continue to experience low self-efficacy inparticipating in their own treatment planning. Additionally, providers (e.g., psychiatrists, community mental health workers, peer specialists, etc.) often struggle to identify concrete ways to incorporate PCCP principles into their daily practice. The Center for Social Innovation (C4) and Yale University's Program for Recovery and Community Health (PRCH) propose to adapt PRCH's field-tested PCCP content into Recovery Roadmap: A Collaborative Tool for Person-Centered Care Planning, a highly interactive web-based tool to support a collaborative process of person-centered recovery planning for consumers and providers. The specific aims of this project are to: 1) create the Recovery Roadmap toolkit; 2) determine the feasibility of the Recovery Roadmap to improve mental health care for consumers; and 3) explore the product's commercial potential. The central component of the Recovery Roadmap is an innovative web-based tool that guides people in recovery to create an individual recovery plan through a series of engaging multimedia, peer-led exercises to identify priorities and life goals. A complementary component educates providers and supports implementation of PCCP through interactive, case-based video vignettes that simulate PCCP interactions. The two tools - which can be accessed on computers, mobile devices, and tablets - work in tandem to support the overall consumer-provider relationship and create a collaborative, person-centered care planning process. C4 will conduct a phase one study to determine the feasibility of conducting a larger relative effectiveness trial. We will pilt this tool through a convenience sample in two community mental health centers in Texas, which will be randomized into two conditions: 1) Recovery Roadmap tool only (n=15 providers),and 2) Recovery Roadmap tool preceded by standard on-site PCCP training (n=15 providers), with each provider recruiting two consumers on their caseload to pilot the Recovery Roadmap tool (n=60 consumers). Data sources will include pre-, post-, and three-month follow-up surveys, focus group discussions, and key informant interviews to capture attitudes, beliefs, knowledge, self-efficacy, perceptions of the consumer-provider relationship, and marketability. Data will allow us to hone product usability, studydesign, and hypotheses to be tested in a phase two study. Finally, we will conduct a market analysis and develop preliminary marketing and pricing strategies. PUBLIC HEALTH RELEVANCE PUBLIC HEALTH RELEVANCE: People in recovery from serious mental illness are often excluded from making decisions about their own mental health care, and providers struggle to identify concrete ways to make their services person centered and recovery oriented, leading to high levels of service disengagement. We propose to develop Recovery Roadmap: A Collaborative Multimedia Tool for Person-Centered Care Planning to promote widespread use of Person-Centered Care Planning (PCCP), an evidence-based approach designed to maximize the choices and ownership that consumers have over their own treatment process. This interactive, web-based tool will support a collaborative process of recovery planning by helping consumers create individual recovery plans, building concrete skills in PCCP implementation for providers, and ultimately improving mental health outcomes for consumers.

Principal Investigator:

Wayne A. Centrone
617-467-6014
wcentrone@center4si.com

Business Contact:

Jeffrey Olivet
617-467-6014
jolivet@center4si.com
Small Business Information at Submission:

CENTER FOR SOCIAL INNOVATION, LLC
200 Reservoir Street Needham, MA 02494-

EIN/Tax ID: 187076304
DUNS: N/A
Number of Employees: N/A
Woman-Owned: Yes
Minority-Owned: No
HUBZone-Owned: No