Amplified Attention Training (AAT) for the Treatment of Hemispatial Nelgect
DESCRIPTION (provided by applicant): The goal of the current project is to revise a prototype of a computerized attention training program (Amplified Attention Training, AAT) for hemispatial neglect completed in Phase I, and conduct a multi-site, randomized, controlled trial to establish efficacy in this population. As a group, patients with hemispatial neglect tend to have poorer long-term prognosis and are more likely to require managed care than other patient groups with lesions of comparable size. Our recent studies are among the first to demonstrate that AAT, targeting sustained attention and vigilance deficits, can produce lasting benefits. The overall goal of the current project is to measure 3 co-primary outcomes: attention, executive function and functional capacity. Evidence from our Phase I trial shows that AAT can improve attention and executive function deficits common to hemispatial neglect. At the completion of this project we will have outcomes data sufficient for submission to the FDA for clearance as a medical device indicated for cognitive enhancement in hemispatial neglect (ICD-9 Code 781.8). PUBLIC HEALTH RELEVANCE PUBLIC HEALTH RELEVANCE: The goal of this project is to revise a prototype of a computerized cognitive training program (Amplified Attention Training, AAT) for patients with hemispatial neglect completed in Phase I, and conduct a multi-site, randomized controlled trial to demonstrate efficacy. This is important because this large patient population suffers from poor prognosis and a lack of viable treatment options.
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BRAIN PLASTICITY, INC.
625 Market St. Ste 610 SAN FRANCISCO, CA 94105-
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