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Anastomotic Device for Large Vascular Grafts

Award Information

Agency:
Department of Health and Human Services 		Branch:
N/A 		Award ID:
93962 		Program Year/Program:
2009 / SBIR
Agency Tracking Number:
HL096198 		Solicitation Year:
N/A 		Solicitation Topic Code:
N/A 		Solicitation Number:
N/A
Small Business Information
ABIOMED, INC.
22 CHERRY HILL DRIVE DANVERS, MA 01923-
View profile »
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
 
Phase 1
Fiscal Year: 2009
Title: Anastomotic Device for Large Vascular Grafts
Agency: HHS
Contract: 1R43HL096198-01
Award Amount: $99,650.00
 

Abstract:

DESCRIPTION (provided by applicant): The objective of this proposed program is to develop a general purpose anastomotic device for large vessels and vascular grafts, based on a novel stapler design. The use of the device can provide an alternative procedur e to the current manual suturing methods, with the potential of yielding anastomoses having better and more reproducible performance, and with reduced cross-clamping or bypass time requirements. The immediate application of this device is in making an end- to-side anastomosis between a graft/cannula and the aorta, for example, as the outflow conduit for a VAD. Under Phase I of the program, a feasibility prototype will be designed, fabricated, and characterized via both ex vivo and acute in vivo studies. Base d upon the success of our Phase I studies, Phase II of the program would focus on the development of a tool with integrated functions, chronic in vivo studies for biocompatibility, and design optimization for ease of use and manufacturing. PUBLIC HEALTH RE LEVANCE: The stapler will improve the quality of large vascular anastomoses and reduce the operating time requirements. There are numerous surgical applications that could benefit from a rapid and repeatable method of placing large (i.e. greater than 5 mm diameter) synthetic vascular grafts, especially a method that reduces the rate of bleeding complications. These include ventricular assist device (VAD) implantation, arteriovenous (AV) fistula placement for renal dialysis, aortic arch reconstruction, and a bdominal aortic aneurysm (AAA) repair. This vascular stapler may be applicable to 100,000 procedures per year in the U.S. alone.

Principal Investigator:

Hong Zhang

Business Contact:

Kung T. Robert
rstewart@abiomed.com
Small Business Information at Submission:

ABIOMED, INC.
ABIOMED, INC. 22 CHERRY HILL DRIVE DANVERS, MA 01923

EIN/Tax ID: 042743260
DUNS: N/A
Number of Employees: N/A
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No