Nanosphere Beacons for Real-Time Detection In Vivo

Award Information

Agency: Department of Defense	Branch: Defense Advanced Research Projects Agency	Award ID: 68791	Program Year/Program: 2004 / SBIR
Agency Tracking Number: 04SB1-0209	Solicitation Year: N/A	Solicitation Topic Code: N/A	Solicitation Number: N/A

Small Business Information: Accacia International Inc
2113 Wells Branch Parkway Suite 6900 Austin, TX -
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Woman-Owned: No

Minority-Owned: No

HUBZone-Owned: No

Phase 1: Fiscal Year: 2004

Title: Nanosphere Beacons for Real-Time Detection In Vivo

Agency / Branch: DOD / DARPA

Contract: W31P4Q-04-C-R232

Award Amount: $98,998.00

Abstract:
Current techniques for real-time detection of signaling pathways in live cells are limited. Accacia International LLC, will develop better strategies by combining the signaling properties of molecular beacons and aptamer beacons with the advantages of quantum dot photoluminescence to produce quantum dot beacons (QDBs). In order to demonstrate the potential of these novel signaling nanoparticles, Accacia will generate QDBs targeting both mRNA and protein targets. The designs will be tested both in vitro and in vivo. These experiments should provide a solid foundation for the future design and generation of additional QDBs which will potentiate parallel detection of all the components of a cell signaling cascade.

Principal Investigator:
Eulalia Sequeira
President
5127841861
bioaid@austin.rr.com

Business Contact:
Eulalia Sequeira
President
5127841861
bioaid@austin.rr.com

Small Business Information at Submission:

ACCACIA INTERNATIONAL LLC
1925 Rutland Drive, Suite E Austin, TX 78758

EIN/Tax ID: 742971514

DUNS: N/A

Number of Employees:

Woman-Owned: No

Minority-Owned: No

HUBZone-Owned: No