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Nanosphere Beacons for Real-Time Detection In Vivo

Award Information

Agency:
Department of Defense
Branch:
Defense Advanced Research Projects Agency
Award ID:
68791
Program Year/Program:
2004 / SBIR
Agency Tracking Number:
04SB1-0209
Solicitation Year:
N/A
Solicitation Topic Code:
N/A
Solicitation Number:
N/A
Small Business Information
Accacia International LLC
One Tech Plaza 2113 Wells Branch Parkway, Suite 6900 Austin, TX -
View profile »
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
 
Phase 1
Fiscal Year: 2004
Title: Nanosphere Beacons for Real-Time Detection In Vivo
Agency / Branch: DOD / DARPA
Contract: W31P4Q-04-C-R232
Award Amount: $98,998.00
 

Abstract:

Current techniques for real-time detection of signaling pathways in live cells are limited. Accacia International LLC, will develop better strategies by combining the signaling properties of molecular beacons and aptamer beacons with the advantages of quantum dot photoluminescence to produce quantum dot beacons (QDBs). In order to demonstrate the potential of these novel signaling nanoparticles, Accacia will generate QDBs targeting both mRNA and protein targets. The designs will be tested both in vitro and in vivo. These experiments should provide a solid foundation for the future design and generation of additional QDBs which will potentiate parallel detection of all the components of a cell signaling cascade.

Principal Investigator:

Eulalia Sequeira
President
5127841861
bioaid@austin.rr.com

Business Contact:

Eulalia Sequeira
President
5127841861
bioaid@austin.rr.com
Small Business Information at Submission:

ACCACIA INTERNATIONAL LLC
1925 Rutland Drive, Suite E Austin, TX 78758

EIN/Tax ID: 742971514
DUNS: N/A
Number of Employees:
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No