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IMPROVED NON-INVASIVE BLOOD GLUCOSE MONITORING DEVICE

Award Information

Agency:
Department of Health and Human Services
Branch:
N/A
Award ID:
60821
Program Year/Program:
2002 / SBIR
Agency Tracking Number:
DK059690
Solicitation Year:
N/A
Solicitation Topic Code:
N/A
Solicitation Number:
N/A
Small Business Information
ACIONT, INC.
350 WEST 800 NORTH, STE 320 SALT LAKE CITY, UT 84103-
View profile »
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
 
Phase 1
Fiscal Year: 2002
Title: IMPROVED NON-INVASIVE BLOOD GLUCOSE MONITORING DEVICE
Agency: HHS
Contract: 1R43DK059690-01A1
Award Amount: $140,992.00
 

Abstract:

The accurate measurement of blood glucose concentration is important in the management of diabetes. Current methods of glucose monitoring involve piercing the skin and collecting blood samples for analysis up to four times daily or more. Even the non-invasive Glucowatch tm glucose monitoring system requires twice daily blood collection for calibration. This original, innovative invention will decrease and maintain the electrical resistance of the skin at a constant level. This allows for a controlled, increased passive or electroosmoticatly driven migration of glucose outwardly through the skin into a biosensor for analysis. By creating a constant permeability and avoiding a capacitance effect, we will be able to reproducibly extract and analyze glucose through the skin, minimizing the need for frequent calibration. Our long-term goal is to commercialize an iontophoretic device that will allow for the accurate and reproducible extraction of glucose from the skin or underlying subcutaneous space. Phase I research will study the linearity between glucose extraction and donor solution concentration in vitro and in vivo and demonstrate the advantage of our approach over the Glucowatch tm We will study glucose flux through human epidermis using a variety of protocols to optimize stratum corneum permeation enhancement and minimize intra- and inter-subject variability.

Principal Investigator:

Abdelhalim Ghanem
8013593461
ADMIN@ACIONT.COM

Business Contact:

Higuchi I
8013593461
ACIONT@NETWORLD.COM
Small Business Information at Submission:

ACIONT, INC.
ACIONT, INC. 350 WEST 800 NORTH, STE 250 SALT LAKE CITY, UT 84103

EIN/Tax ID: 943356125
DUNS: N/A
Number of Employees: N/A
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No