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Development of a Novel Acoustic Resuscitation Monitor

Award Information

Department of Health and Human Services
Award ID:
Program Year/Program:
2005 / SBIR
Agency Tracking Number:
Solicitation Year:
Solicitation Topic Code:
Solicitation Number:
Small Business Information
Active Signal Technologies, Inc.
Hammonds South, Unit Q 611 North Hammonds Ferry Road Linthicum Heights, MD -
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Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
Phase 1
Fiscal Year: 2005
Title: Development of a Novel Acoustic Resuscitation Monitor
Agency: HHS
Contract: 1R43HL079716-01A1
Award Amount: $293,252.00


DESCRIPTION (provided by applicant): Currently almost half of all trauma mortality is directly or indirectly attributable to hemorrhagic shock, accounting for more than 50,000 deaths yearly in the U.S. and hundreds of billions of dollars in economic costs. Active Signal Technologies proposes to develop an Acoustic Resuscitation Monitor (ARM) for enabling non-invasive assessment of systemic perfusion in real time, with the ultimate goal of developing a device that can continuously monitor shock and resuscitation in the field. As no such device exists and current perfusion tests have significant lag time, ARM can significantly improve patient outcome and lower costs both for in-hospital (Phase I) and field (Phase II) settings. The ARM technology is based on Active Signal's Brain Acoustic Monitor (BAM) - demonstrated effectively in brain perfusion studies on more than 500 trauma and 100 stroke patients. In Phase I Active Signal with the University of Maryland Shock Trauma Center will conduct feasibility tests on approximately 100 patients with 5 data collection times. Specific aims are to determine the relationship between vasoconstriction as indicated by ARM using pulse-waveform characteristics and systemic perfusion measured by current clinical metrics, and to reconfigure the BAM to monitor vasoconstriction at 3 arterial tree levels.

Principal Investigator:

John M. Sewell

Business Contact:

Arthur Cooke
Small Business Information at Submission:

Active Signal Technologies, Inc.
Active Signal Technologies, Inc. 13025 Beaver Dam Rd Cockeysville, MD 21030

EIN/Tax ID: 521960088
Number of Employees: N/A
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No