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A Client-Accessible Design Interface for Physical Models

Award Information

Agency:
Department of Health and Human Services
Branch:
N/A
Award ID:
70792
Program Year/Program:
2004 / SBIR
Agency Tracking Number:
RR020234
Solicitation Year:
N/A
Solicitation Topic Code:
N/A
Solicitation Number:
N/A
Small Business Information
3D MOLECULAR DESIGNS
1050 N Market St MILWAUKEE, WI 53202-3113
View profile »
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
 
Phase 1
Fiscal Year: 2004
Title: A Client-Accessible Design Interface for Physical Models
Agency: HHS
Contract: 1R43RR020234-01
Award Amount: $149,917.00
 

Abstract:

DESCRIPTION (provided by applicant): An accurate physical model of a protein, based on its atomic coordinate data and created by rapid prototyping technology, is an effective new tool to communicate the essential details of a new structure to the biochemists and molecular biologists who are working to understand the role of that protein in human health and disease. 3D Molecular Designs (3DMD) has contributed to the development of this technology by creating software (RP-RasMol) that directly outputs the file format needed by rapid prototyping machines. As more researchers and educators become aware of the availability of these physical models, there is a growing need for new software that will allow these clients to play a more active role in the design of the model. We propose to build a Web-based, goal-oriented Client-Accessible Design Interface for Molecules (CADIMol) that will meet this need. CADI-Mol will employ the open-source software Jmol to display interactive 3D molecular models in any popular browser, and in all common operating systems. Clients will initially choose from four basic model formats, and then refine their design in a series of steps that each provide immediate visual feedback. The design will then be automatically ported to RP-RasMol where it will be converted into a rapid prototyping format and further optimized by 3DMD staff designers. The final optimized design will then be presented back to the client in a Design Review Interface for final approval. We believe that immediate visual feedback, combined with the power of interactive 3D visualization, will ultimately produce a design that accurately represents the client's own mental image of the physical model, but at a fraction of the effort currently required of 3DMD staff designers. The effect of this innovation will be the broader application of rapid prototyping technologies to produce physical models of molecular structures that can be used as both "thinking tools" and "communication tools" by scientists and educators in structure-based research labs.

Principal Investigator:

Timothy Driscoll
4147746562
driscoll@mose.edu

Business Contact:


4147746562
Small Business Information at Submission:

3D MOLECULAR DESIGNS
3D MOLECULAR DESIGNS 2223 N 72ND ST WAUWATOSA, WI 53213

EIN/Tax ID: 391981690
DUNS: N/A
Number of Employees: N/A
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No