USA flag logo/image

An Official Website of the United States Government

THE SURFACE PLASMON IMMUNOASSAY FOR MEASUREMENT OF HCG

Award Information

Agency:
Department of Health and Human Services
Branch:
N/A
Award ID:
16491
Program Year/Program:
1991 / SBIR
Agency Tracking Number:
16491
Solicitation Year:
N/A
Solicitation Topic Code:
N/A
Solicitation Number:
N/A
Small Business Information
Adelphi Technology, Inc.
2003 East Bayshore Rd. Redwood City, CA 94063-4121
View profile »
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
 
Phase 1
Fiscal Year: 1991
Title: THE SURFACE PLASMON IMMUNOASSAY FOR MEASUREMENT OF HCG
Agency: HHS
Contract: N/A
Award Amount: $49,963.00
 

Abstract:

THE SURFACE PLASMON RESONANCE PHENOMENON WILL BE EXPLORED TO DEVELOP A QUANTITATIVE, SENSITIVE, ASSAY SYSTEM FOR REPRODUCTIVE HORMONES OF CLINICAL INTEREST. THE APPROACH CAN ATTAIN, WITH RELATIVELY INEXPENSIVE INSTRUMENTATION, A SENSITIVITY LIMIT COMPARABLE TO EXISTING ASSAY METHODOLOGIES, WITHOUT THE USE OF DYES, RADIOISOTOPES OR ENZYMES FOR SPECIFIC SIGNAL GENERATION. PART OF THE PHASE I RESEARCH WORK WILL ENTAIL CHOICE OF REAGENTS AND DEVELOPMENT OF A COMPACT OPTICAL INSTRUMENT FOR PERFORMING HORMONE QUANTIFICATIONS OF SERUM SAMPLES USING THE SURFACE PLASMON IMMUNOASSAY (SPI). DURING THIS STAGE OF THE RESEARCH, HUMAN CHORIONIC GONADOTROPIN (HCG), WILL BE USED AS A MODEL HORMONE TO CHARACTERIZE THE ASSAY PERFORMANCE IN TERMS OF SENSITIVITY, SPECIFICITY, ACCURACY, AND REPRODUCIBILITY. IN THE PHASE II STUDY, THE APPROACH WILL BE EXTENDED TO INCLUDE OTHER HORMONES OF CLINICAL INTEREST AND THE POSSIBILITY FOR REAL-TIME HORMONE QUANTIFICATION WILL BE INVESTIGATED.

Principal Investigator:

Fontana, Eduardo
Principal Investigator
4153287337

Business Contact:

1 r43 hd28542-01
Small Business Information at Submission:

Adelphi Technology
285 Hamilton Avenue, Suite 430 Palo Alto, CA 94301

EIN/Tax ID:
DUNS: N/A
Number of Employees: N/A
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No