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SBIR Phase II: X-ray Microscope for In-Vivo Biological Imaging

Award Information

Agency:
National Science Foundation
Branch:
N/A
Award ID:
63399
Program Year/Program:
2003 / SBIR
Agency Tracking Number:
0319668
Solicitation Year:
N/A
Solicitation Topic Code:
N/A
Solicitation Number:
N/A
Small Business Information
Adelphi Technology, Inc.
2003 East Bayshore Rd. Redwood City, CA 94063-4121
View profile »
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
 
Phase 1
Fiscal Year: 2003
Title: SBIR Phase II: X-ray Microscope for In-Vivo Biological Imaging
Agency: NSF
Contract: 0450518
Award Amount: $100,000.00
 

Abstract:

This Small Business Innovation Research (SBIR) Phase II project aims to develop a sub-micron x-ray tomography scanner capable of providing in-vivo and high resolution images of specimens from mice to bacteria. In this era of molecular medicine, where disease and developmental disorders are being re-defined by their peculiar molecular, genetic or cellular profiles, there exists a significant disparity between the type of information gleaned from histological methods and that obtained from conventional non-invasive imaging modalities. With a resolution that is better than these imaging modalities and more than ten times higher than that of current x-ray imaging systems, the proposed device will generate images of development and disease not possible by current methods. The Phase II research will concentrate on the development of the x-ray optical system, including beam conditioning, tomographic imaging capability, and the imaging x-ray lens, and will result in a table-top commercial prototype computerized tomographic imager with 400 nm resolution. The commercial application of this project will be in the area of medical research. When compared to existing in-vivo imaging technologies, the higher resolution of the proposed x-ray imager will translate to improved sensitivity and specificity of morphologic changes associated with growth and disease. Researchers will be able to use this tool for investigations of a number of medical conditions, including tumor angiogenesis, atherosclerosis, osteoporosis and arthritis.

Principal Investigator:

Charles K. Gary
Dr
6505989800
cgary@adelphitech.com

Business Contact:

Charles K. Gary
Dr
6505989800
cgary@aldelphitech.com
Small Business Information at Submission:

Adelphi Technology, Inc
981-B Industrial Road San Carlos, CA 94070

EIN/Tax ID:
DUNS: N/A
Number of Employees:
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No