DESCRIPTION:( provided by applicant) Fatigue management is a critical public health concern in today's 24-hour society. Fatigue-related accidents and decreased productivity cost the U.S. over $77 billion each year. The ability to objectively and reliably rnonitor fatigue levels in… More

The proposed research demonstrates the feasibility for two innovative evaluation procedures for diagnostic screening and treatment outcome assessment for sleep apnea (SA). The Alertness for diagnostic screening and treatment outcome assessment for sleep apnea (SA). The Alertness Profiler (AP)… More

Sleep Apnea (SA) is the most common disorder observed in the practice of sleep medicine and is responsible for more mortality and morbidity than any other sleep disorder. Although more than 4% of the population is estimated to suffer from SA, the majority are undiagnosed and untreated. This proposal… More

DESCRIPTION (Applicant's abstract): The proposed research evaluates the efficacy of the Alertness Profiling (AP) System as a method for objectively quantifying alertness in Sleep Apnea (SA) patients. The AP simultaneously measures electroencephalographic (EEG) indices and performance… More

Phase II completes development of the Apnea Risk Evaluation System (ARES), an integrated method, including: a) a physiological data acquisition device, easily self-applied to the forehead and comfortably worn throughout the night to collect data to screen for SA (Sp02, pulse, snoring and head… More

Phase II completes development of the Apnea Risk Evaluation System (ARES), an integrated method, including: a) a physiological data acquisition device, easily self-applied to the forehead and comfortably worn throughout the night to collect data to screen for SA (Sp02, pulse, snoring and head… More

DESCRIPTION (Applicant's abstract): The proposed research evaluates the efficacy of the Alertness Profiling (AP) System as a method for objectively quantifying alertness in Sleep Apnea (SA) patients. The AP simultaneously measures electroencephalographic (EEG) indices and performance… More

DESCRIPTION (provided by applicant): The Apnea Risk Evaluation System (ARES) is an inexpensive, in-home method assessing for sleep-disordered breathing. ARES utilizes expert software to integrate analysis of nocturnal oxygen saturation, pulse rate, snoring sounds, head position/movement recordings… More

DESCRIPTION (provided by applicant): Obstructive Sleep Apnea (OSA) is the most common disorder observed in the practice of sleep medicine and is responsible for more mortality and morbidity than any other sleep disorder. OSA causes daytime drowsiness and cognitive impairment, and has been associated… More

DESCRIPTION (provided by applicant): Tobacco dependence is the most common substance abuse disorder and the leading preventable cause of death in the United States. More than three million lives a year worldwide are lost due to smoking. Alterations in neurocognitive function play a major role in… More

DESCRIPTION (provided by applicant): Obstructive Sleep Apnea (OSA) is the most common disorder observed in the practice of sleep medicine and is responsible for more mortality and morbidity than any other sleep disorder. OSA causes daytime drowsiness, and has been associated with hypertension,… More

DESCRIPTION (provided by applicant): Obstructive Sleep Apnea (OSA), a highly prevalent, under-diagnosed condition is responsible for more mortality and morbidity than any other sleep disorder and has been identified as a major public health concern. Pediatric OSA is also widespread with an estimated… More

Military operations require sustained performance in challenging environments where vigilance, memory, decision-making are impaired by sleep deprivation and poor sleep quality. Evidence reveals that "power-naps" (10-20 minutes) taken throughout the day can ameliorate some effects of sleep… More

DESCRIPTION (provided by applicant): Alterations in neurocognitive function play a major role in numerous sleeps, neurological and psychiatric disorders and can have a significant impact on quality of life, treatment efficacy, rehabilitation and ability to function at work and in normal daily… More

DESCRIPTION (provided by applicant): Obstructive Sleep Apnea (OSA), a highly prevalent, under-diagnosed disorder affecting over 18 million Americans, is responsible for more mortality and morbidity than any other sleep disorder. Dentists are increasingly i nvolved with the treatment of OSA with oral… More

According to Department of Homeland Security (DHS), over 700 million pieces of baggage are screened for potential threats in the U.S. every year. Training methods for DHS screeners rely on conventional classroom instruction and on-the-job mentoring. By definition, a screener's work is challenging… More

Contemporary warfighters are required to continually acquire new skills across diverse knowlege domains ranging from the operation of new equipment to marksmanship to cultural diplomacy. The investigators propose to integrate neuroscience-based evaluatio

Military operations require sustained cognitive performance in challenging environments. Situational awareness, vigilance, memory, decision-making, and other neurocognitive processes are all impacted by poor sleep quality, sleep deprivation and accumulating sleep debt with potentially detrimental… More

Advanced Brain Monitoring (ABM) developed patented low cost, easy-to-use, portable systems to monitor and interpret physiological signals, including the brain''s electrical activity (EEG) and cardiac activity. These technologies can be applied in real-time or off-line and have proven useful in… More

The recent military buildup in Iraq and Afghanistan with its associated stressors of warfare have resulted in a significant increase in new cases of posttraumatic stress disorder (PTSD). Sleep disturbances comprise prominent features of PTSD and have been suggested to have a pathogenic role in the… More

It is well known that the brain is the organ most sensitive to ischemia/hypoxia. Noninvasive continuous monitoring of cerebral blood flow autoregulation, cerebrovascular reactivity and related phenomena such as cerebral vasospams in combat casualties could guide clinicians/medics in adjusting the… More

DESCRIPTION (provided by applicant): Neurologic disorders frequently affect everyday functioning. However, clinicians and researchers have had limited success in predicting who will, or will not, succeed at real-world tasks, since most assessments rely ontesting from in a controlled environment… More

Under this Small Business Innovation Research (SBIR) Phase I project, Research Topic 137, "Quantification of Behavioral and Physiological Effects of Drugs Using a Mobile Scalable Device", the contractor shall create and evaluate the Mobile-Alertness-Memory-Profiler (M-AMP); an… More

It is well known that the brain is the organ most sensitive to ischemia/hypoxia. Noninvasive continuous monitoring of cerebral blood flow autoregulation, cerebrovascular reactivity and related phenomena such as cerebral vasospams in combat casualties could guide clinicians/medics in adjusting the… More