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Company Information:

Company Name: ADVANCED CIRCULATORY SYSTEMS, INC.
City: Roseville
State: MN
Zip+4: -
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
Website URL: N/A
Phone: N/A

Award Totals:

Program/Phase Award Amount ($) Number of Awards
SBIR Phase I $1,659,666.00 11
SBIR Phase II $6,820,283.00 7

Award List:

N/A

Award Year / Program / Phase: 2000 / SBIR / Phase I
Agency: HHS
Principal Investigator: Keith G. Lurie
Award Amount: $100,000.00
Abstract:
Not Available A lightweight, low power micro-cone penetrometer (MCPT) system is proposed to meet NASA¿s need for better subsurface exploration devices. The low cost MCPT will consist of characterization and sampling probes driven into the ground by low reaction force

IMPEDANCE THRESHOLD VALVE FOR IMPROVING STANDARD CPR

Award Year / Program / Phase: 2002 / SBIR / Phase I
Agency: HHS
Principal Investigator: Keith G. Lurie
Award Amount: $0.00
Abstract:
Despite standard CPR, the vast majority of patients in cardiac arrest never survive to hospital discharge. Simple and effective methods for improving the efficacy of CPR are needed. The inspiratory threshold valve (ITV(tm)) is a new device designed to increase negative intrathoracic pressure and… More

Noninvasive Treatment of Hemorrhagic Shock

Award Year / Program / Phase: 2004 / SBIR / Phase I
Agency / Branch: DOD / ARMY
Principal Investigator: Keith Lurie, Chief Medical Officer
Award Amount: $69,957.00
Abstract:
Hemorrhagic shock is the leading cause of death in combat injuries. This application focuses on a novel way to treat hemorrhagic shock using a new device called the inspiratory impedance threshold device (ITD). The ITD increases blood pressure and survival rates in animals in hemorrhagic shock. … More

Novel device for improving standard CPR outcomes

Award Year / Program / Phase: 2004 / SBIR / Phase I
Agency: HHS
Principal Investigator: Keith G. Lurie
Award Amount: $99,947.00
Abstract:
DESCRIPTION (provided by applicant): Despite the widespread practice of basic and advanced life support, the vast majority of patients in cardiac arrest never survive to hospital discharge. The inherent mechanical inefficiencies of standard CPR limit the potential of even the most highly skilled… More

Noninvasive Treatment of Hemorrhagic Shock

Award Year / Program / Phase: 2005 / SBIR / Phase II
Agency / Branch: DOD / ARMY
Principal Investigator: Keith Lurie, Chief Medical Officer
Award Amount: $729,944.00
Abstract:
Shock secondary to acute blood loss remains the number one cause of death for our soldiers. Furthermore, heat shock and dehydration remain a common cause of cardiovascular collapse for our military personnel, especially as operations move increasingly into desert combat. The main objective of this… More

Intrathoracic Pressure Regulator for Resuscitation

Award Year / Program / Phase: 2005 / SBIR / Phase I
Agency: HHS
Principal Investigator: Keith G. Lurie
Award Amount: $295,797.00
Abstract:
DESCRIPTION (provided by applicant): Traumatic injury remains the number one cause of death for Americans between 1 and 44 years of age. The economic consequences of trauma related injuries are estimated at over 44 billion dollars in direct costs and over 400 billion dollars per year in… More

Novel device for improving standard CPR outcomes

Award Year / Program / Phase: 2006 / SBIR / Phase II
Agency: HHS
Principal Investigator: Keith G. Lurie
Award Amount: $980,719.00
Abstract:
DESCRIPTION (provided by applicant): The goal of this SBIR Phase II application is to continue the development and evaluation of a novel device designed to increase the efficiency of manual CPR. This hand-held lightweight device, termed the ErgoPad, helps to transform the thorax into a bellows… More

Inspiratory Impedance as a Treatment for Traumatic Brain Injury

Award Year / Program / Phase: 2006 / SBIR / Phase I
Agency / Branch: DOD / ARMY
Principal Investigator: Keith Lurie, Chief Medical Officer
Award Amount: $69,731.00
Abstract:
Traumatic head and neck injuries account for 16-33% of all war-related injuries and are a leading cause of mortality upon evacuation to a definitive care setting. This application is focused on treating one of the most important determinants of outcome from severe head injury, the degree and… More

Novel non-invasive device for treatment of elevated intracranial pressures

Award Year / Program / Phase: 2006 / SBIR / Phase I
Agency: HHS
Principal Investigator: Keith G. Lurie
Award Amount: $153,176.00
Abstract:
DESCRIPTION (provided by applicant): Despite advances in the treatment of patients with shock and head injuries, the combination of traumatic brain injury and hemorrhagic shock is the leading cause of death and disability in children and adults in their most productive years. An estimated 1.6… More

Resuscitation--impedance threshold devices in pediatrics

Award Year / Program / Phase: 2006 / SBIR / Phase I
Agency: HHS
Principal Investigator: Keith G. Lurie
Award Amount: $317,675.00
Abstract:
DESCRIPTION (provided by applicant): Traumatic injury and hypovolemic shock are leading causes of death in children worldwide. Rapid, large volume crystalloid infusion and positive intrathoracic pressure ventilation resuscitation strategies often increase morbidity and mortality following… More

Novel non-invasive treatment for hypotension during hemodialysis

Award Year / Program / Phase: 2007 / SBIR / Phase I
Agency: HHS
Principal Investigator: Anja K. Metzger
Award Amount: $177,040.00
Abstract:
DESCRIPTION (provided by applicant): Intradialytic hypotension (IDH) is associated with increased morbidity and mortality and causes delays in patient care during and immediately after dialysis. It remains one of the most vexing problems associated with di alysis therapy, occurring in approximately… More

Impedance Threshold Value for Improving Standard CPR

Award Year / Program / Phase: 2008 / SBIR / Phase II
Agency: HHS
Principal Investigator: Keith G. Lurie
Award Amount: $1,490,894.00
Abstract:
DESCRIPTION (provided by applicant): Despite the widespread practice of basic and advanced life support, over 1000 patients die each day in the United States from an out-of-hospital cardiac arrest. Even though they receive standard cardiopulmonary resuscit ation (sCPR) the average national survival… More

Inspiratory Impedance as a Treatment for Traumatic Brain Injury

Award Year / Program / Phase: 2008 / SBIR / Phase II
Agency / Branch: DOD / ARMY
Principal Investigator: Keith Lurie, Chief Medical Officer
Award Amount: $729,863.00
Abstract:
Traumatic head and neck injuries account for 16-33% of all war-related injuries and are a leading cause of mortality upon evacuation to a definitive care setting. Therapeutic advances are urgently needed for these soldiers. This application is focused on treating one of the most important… More

Non-invasive Extra-Corporeal Circulator for Prolonged Resuscitation

Award Year / Program / Phase: 2009 / SBIR / Phase I
Agency: HHS
Principal Investigator: Keith G. Lurie
Award Amount: $194,873.00
Abstract:
DESCRIPTION (provided by applicant): Based upon newly discovered mechanisms to enhance circulation during CPR, the goal of this SBIR phase 1 application is to develop a comprehensive and novel non-invasive extracorporeal automated circulatory assist device to normalize blood flow during cardiac… More

Intrathoracic Pressure Regulation for the Treatment of Septic Shock

Award Year / Program / Phase: 2009 / SBIR / Phase I
Agency: HHS
Principal Investigator: Keith G. Lurie
Award Amount: $181,470.00
Abstract:
DESCRIPTION (provided by applicant): Despite advances in the treatment of patients with sepsis, sepsis remains the second most common cause of death in non-coronary intensive care units and the tenth leading cause of death overall in high-income countries. It has been estimated that gt750,000 cases… More

Novel non-invasive device for treatment of elevated intracranial pressures

Award Year / Program / Phase: 2010 / SBIR / Phase II
Agency: HHS
Principal Investigator: Keith G. Lurie
Award Amount: $843,628.00
Abstract:
DESCRIPTION (provided by applicant): An estimated 1.6 million head injury occurs every year in the United States. Traumatic brain injury affects 3 out of every 1000 Americans each year accounting for as many as 60,000 deaths and an estimated 70,000 to 90,000 patients with permanent neurologic… More

Intrathoracic Pressure Regulator for Resuscitation

Award Year / Program / Phase: 2010 / SBIR / Phase II
Agency: HHS
Principal Investigator: Keith G. Lurie
Award Amount: $862,215.00
Abstract:
DESCRIPTION (provided by applicant): The goal of this SBIR Phase 2 application is to continue the development and evaluation the intrathoracic pressure regulator (ITPR), intended to increase circulation and blood pressure clinically significant states of h ypotension, including cardiac arrest and… More

Resuscitation using novel impedance threshold devices in pediatrics

Award Year / Program / Phase: 2012 / SBIR / Phase II
Agency: HHS
Principal Investigator: Keith G. Lurie – 612-986-3917
Award Amount: $1,183,020.00
Abstract:
DESCRIPTION (provided by applicant): Traumatic injury and hypovolemic shock are leading causes of death in children worldwide. Rapid, large volume crystalloid infusion and positive intrathoracic pressure ventilation resuscitation strategies often increasemorbidity and mortality following hemorrhage.… More