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Modular Perfusion Bioreactor for Tissue Engineering

Award Information

Department of Defense
Office of the Secretary of Defense
Award ID:
Program Year/Program:
2010 / SBIR
Agency Tracking Number:
Solicitation Year:
Solicitation Topic Code:
OSD 09-H11
Solicitation Number:
Small Business Information
Resodyn Corporation
130 North Main Street Suite 600 Butte, MT 59701-
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Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
Phase 1
Fiscal Year: 2010
Title: Modular Perfusion Bioreactor for Tissue Engineering
Agency / Branch: DOD / OSD
Contract: W81XWH-10-C-0203
Award Amount: $100,000.00


This project will develop and demonstrate a prototype Modular Perfusion Bioreactor (MPB) for tissue engineering applications. While many unique styles of bioreactors have been proposed for various types of stem cell and tissue cultures, there is not a single, easy-to-use device that accommodates the multiple diverse needs of multiple tissue culture types.. In order to take advantage of recent advances in stem cell culture, biomaterials, and tissue engineering techniques, Resodyn Corporation proposes to develop, design, fabricate, and test a multi-functional bioreactor platform system. As a starting point for this multi-functional system, Resodyn Corporation will use its highly scalable (50-1,500ml) and successful (>1x108 cells/ml) hypoxia perfusion bioreactor. The focus of the proposed work will be to design additional culture modules that can be plugged into an advanced platform system developed by Resodyn Corporation. Modules that allow the culture of cellular monolayers, encapsulated cells, microcarrier-attached cells, and cells attached to scaffolds of various types will be developed and tested for feasibility and applicability. The MPB system has significant long-term commercial potential both in the laboratory and the clinic as a tool to facilitate the translation of stem cell developments into practical replacement tissues for neural, hematopoietic, and mesenchymal lineages.

Principal Investigator:

Todd McAdams
Principal Investigator

Business Contact:

Lawrence C. Farrar
Small Business Information at Submission:

Resodyn Corporation
130 North Main Street Suite 600 Butte, MT 59701

EIN/Tax ID: 810528815
Number of Employees:
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No