USA flag logo/image

An Official Website of the United States Government

In vitro Models Suitable for High-throughput Screening of Drug Toxicities in…

Award Information

Agency:
Department of Defense
Branch:
Office for Chemical and Biological Defense
Award ID:
96630
Program Year/Program:
2010 / SBIR
Agency Tracking Number:
C101-103-0113
Solicitation Year:
N/A
Solicitation Topic Code:
CBD 10-103
Solicitation Number:
N/A
Small Business Information
Nico Technologies Corp.
401 W. Morgan Road, Ann Arbor, MI -
View profile »
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
 
Phase 1
Fiscal Year: 2010
Title: In vitro Models Suitable for High-throughput Screening of Drug Toxicities in Human Tissues
Agency / Branch: DOD / CBD
Contract: HDTRA1-10-P-0037
Award Amount: $69,869.00
 

Abstract:

The drug R&D cycle is long and very expensive. In many ways, this status quo can no longer be sustained. One of the reasons for such great cost is that the vast majority of drug candidates are screened out at the stages of animal and human trials. More efficient methods of testing of drugs at the stage of ex-vivo studies, which are substantially less expensive than animal and human testing cycles, will lead to improvement of the success rate of preclinical trials, acceleration of drug discovery, reduction of the cost of pharmaceutical development, and better drugs. In this Phase I SBIR project involving a start-up company Nico Technology Corporation (NTCorp) and the University of Michigan, we propose the development of a new type of 3D scaffold that can (1) rectify the problems of existing 3D matrixes and (2) provide the pharmaceutical industry the possibility to develop convenient and reliable protocols for drug assessment in organ replicas, and in particular ex-vivo bone marrow construct.

Principal Investigator:

Kelechi Anyaogu
Senior Scientist
7349458131
kelechi@nico-technologies.com

Business Contact:

Elvira Stesikova
Project Manager
7349458131
elvira@nico-technologies.com
Small Business Information at Submission:

Nico Technologies Corp.
401 W. Morgan Road, Ann Arbor, MI 48108

EIN/Tax ID: 352267481
DUNS: N/A
Number of Employees:
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No