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SBIR/STTR Phase II: Automated Analyzer for Drug Delivery Systems

Award Information

National Science Foundation
Award ID:
Program Year/Program:
2002 / SBIR
Agency Tracking Number:
Solicitation Year:
Solicitation Topic Code:
Solicitation Number:
Small Business Information
Aerodyne Research, Inc.
45 Manning Road Billerica, MA 01821-
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Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
Phase 2
Fiscal Year: 2002
Title: SBIR/STTR Phase II: Automated Analyzer for Drug Delivery Systems
Agency: NSF
Contract: N/A
Award Amount: $499,378.00


This Small Business Innovation Research Phase II project will develop a new analytical tool for characterizing drug delivery aerosols and powders. This instrument will be based on a previously developed aerosal mass spectrometer that provides real-time size distribution and chemical composition measurements for aerosol particles. During Phase I research, a new inlet for the aerosol mass spectrometer, allowing detection of particles in the size range relevant to inhalable drug delivery aerosols and powders (2 to 10 mm in diameter), was successfully developed. The key objectives of the Phase II project are : (a) to further improve the collection efficiency for particles in the 2 to 10 mm diameter size range ; (b) to design and construct a sampling apparatus that conforms to Food and Drug Administration (FDA) and U. S. Pharmacopeia Convention (USP) guidelines for sampling drug delivery aerosols from metered dose inhalers (MDIs) and dry powder inhalers (PDIs); and (c)to develop and to validate an analytical method that meets FDA standards. The commercial applications of this project will be in the area of drug delivery.

Principal Investigator:

Douglas Worsnop

Business Contact:

Small Business Information at Submission:

Aerodyne Research Inc
45 Manning Road Billerica, MA 01821

Number of Employees: N/A
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No