DESCRIPTION (Adapted from the Investigator's Abstract): The chlorofluorocarbon (CFC) propellants currently being used in metered dose inhalers for pulmonary drug delivery are being phased out due to their high ozone depletion potential. An international pharmaceutical industry… More

DESCRIPTION (Applicant's abstract): Asthma is one of the most common and costly illnesses in the United States, and drug formulation delivered via metered inhalers (MDIs) represent the primary treatment method for asthma sufferers. A key current issue in this arena is that the chlorofluorocarbon… More

DESCRIPTION (provided by applicant): Delivery of anticancer drugs as inhaled aerosols is an attractive possibility for the treatment of lung cancer. Many of the agents that exhibit inhibitory activity towards cancer cell growth are lipophilic, including topotecan, taxol, taxotere, and etoposide.… More

DESCRIPTION (provided by applicant): Lung cancer kills over 1.3 million per year worldwide. Conventional oral and i.v. chemotherapies used today have toxic effects in many organs besides the lungs. Consequently, doses are limited when treating lung cancer to an extent that it is often not effective.… More

DESCRIPTION (provided by applicant): Asthma is one of the most common and costly illnesses in the US, with over 20 million Americans suffering from asthma with an annual societal cost of over 18 billion. Sadly, about 5000 Americans die every year from ast hma, even though most asthma death is… More

Worldwide fossil-fuel consumption is skyrocketing, creating major social, political, economic, and environmental problems for the US and once again throwing the spotlight upon the urgent need for boosting renewable energy sources, including biodiesel. However, key technical and economic challenges… More

DESCRIPTION (provided by applicant): Malaria sickens over 100 million people each year. The vast majority of the victims live in endemic, tropical countries. Aggressive mosquito eradication programs in the 1940s essentially ended the incidence of locally-a cquired malaria in the US, but resurgence… More

Worldwide fossil-fuel consumption is skyrocketing ¿ creating major social, political, economic, and environmental problems for the U.S. ¿ and once again revealing the urgent need to boost renewable energy sources, including biodiesel. However, key technical and economic challenges continue to… More