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Company Information:

Company Name: AFFOMIX, INC.
City: GUILFORD
State: CT
Zip+4: 06437
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
Website URL: N/A
Phone: N/A

Award Totals:

Program/Phase Award Amount ($) Number of Awards
SBIR Phase I $701,643.00 5
STTR Phase I $100,000.00 1

Award List:

HT-production of Abs using Interaction Trap in Yeast

Award Year / Program / Phase: 2008 / STTR / Phase I
Agency: HHS
Research Institution: N/A
Principal Investigator:
Award Amount: $100,000.00
RI Contact: N/A
Abstract:
DESCRIPTION (provided by applicant): Affomix would like to commercialize antibody chips to enable researchers to study the human proteome. Currently, researchers use gene chips as a surrogate means to estimate the concentration of the vast variety of pro teins in cells and tissues. But given the… More

Microfluidic selection of monoclonal antibodies

Award Year / Program / Phase: 2008 / SBIR / Phase I
Agency: HHS
Principal Investigator:
Award Amount: $111,350.00
Abstract:
DESCRIPTION (provided by applicant): Nearly 20 years ago, partially as a response to leveraging the genomics research the NIH invested in the development of gene array technologies. These gene chips' enabled great breakthroughs in our understanding of the underlying biological processes that occur… More

Emulsion phage display for high-throughput isolation of affinity binders

Award Year / Program / Phase: 2009 / SBIR / Phase I
Agency: HHS
Principal Investigator: Michael P. Weiner
Award Amount: $100,000.00
Abstract:
DESCRIPTION (provided by applicant): We propose to develop an inexpensive high-throughput means of selecting and identifying antibodies to both unmodified and modified protein, peptide, and non-peptide antigens. The specific goals of this proposal are to complete a proof-of-concept using aqueous… More

Development of a method to multiplex ChIP-SEQ and ChIP-chip experiments

Award Year / Program / Phase: 2010 / SBIR / Phase I
Agency: HHS
Principal Investigator: Michael P. Weiner
Award Amount: $96,738.00
Abstract:
DESCRIPTION (provided by applicant): The immediate objective of our research is to generate a method that will enable researchers to multiplex Chromatin ImmunoPreciptation-Sequencing (ChIP-Seq) analysis in a single Next generation DNA sequencing run. In th e to-be-developed method: i) a set of… More

High-throughput screening and identification of scFv antibodies against glycosyla

Award Year / Program / Phase: 2010 / SBIR / Phase I
Agency: HHS
Principal Investigator: Margaret M. Kiss
Award Amount: $193,520.00
Abstract:
DESCRIPTION (provided by applicant): The specific goal of this proposal is to develop a high-throughput method to identify scFv antibodies that recognize post-translationally modified proteins. We propose to complete a proof-of-concept for a new type of af finity screening process based on emulsion,… More

A bifunctional antibody screening system for both phage display and yeast two-hyb

Award Year / Program / Phase: 2010 / SBIR / Phase I
Agency: HHS
Principal Investigator: Michael P. Weiner
Award Amount: $200,035.00
Abstract:
DESCRIPTION (provided by applicant): This is a proposal to establish a proof-of-principle for a vector system to isolate high-affinty antibodies through selective rounds in both yeast and Escherichia coli. Antibodies have quickly become extremely useful as therapeutic medicines to treat a… More