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Company Information:
Name:
AFFOMIX, INC.
Address:
AFFOMIX, INC.
52 LEIGHTON TRAIL
GUILFORD, CT 06437
52 LEIGHTON TRAIL
GUILFORD, CT 06437
Located in HUBZone:
No
Woman-Owned:
No
Minority-Owned:
No
URL:
N/A
Phone:
N/A
Award Totals:
Award List:
HT-production of Abs using Interaction Trap in Yeast
Award Year / Program / Phase:
2008 / STTR / Phase I
Agency:
HHS
Research Institution:
N/A
Principal Investigator:
Award Amount:
$100,000.00
RI Contact:
N/A
Abstract:
DESCRIPTION (provided by applicant): Affomix would like to commercialize antibody chips to enable researchers to study the human proteome. Currently, researchers use gene chips as a surrogate means to estimate the concentration of the vast variety of pro
teins in cells and tissues. But given the… More
Microfluidic selection of monoclonal antibodies
Award Year / Program / Phase:
2008 / SBIR / Phase I
Agency:
HHS
Principal Investigator:
Award Amount:
$111,350.00
Abstract:
DESCRIPTION (provided by applicant): Nearly 20 years ago, partially as a response to leveraging the genomics research the NIH invested in the development of gene array technologies. These gene chips' enabled great breakthroughs in our understanding of the
underlying biological processes that occur… More
Emulsion phage display for high-throughput isolation of affinity binders
Award Year / Program / Phase:
2009 / SBIR / Phase I
Agency:
HHS
Principal Investigator:
Michael P. Weiner
Award Amount:
$100,000.00
Abstract:
DESCRIPTION (provided by applicant): We propose to develop an inexpensive high-throughput means of selecting and identifying antibodies to both unmodified and modified protein, peptide, and non-peptide antigens. The specific goals of this proposal are to
complete a proof-of-concept using aqueous… More
Development of a method to multiplex ChIP-SEQ and ChIP-chip experiments
Award Year / Program / Phase:
2010 / SBIR / Phase I
Agency:
HHS
Principal Investigator:
Michael P. Weiner
Award Amount:
$96,738.00
Abstract:
DESCRIPTION (provided by applicant): The immediate objective of our research is to generate a method that will enable researchers to multiplex Chromatin ImmunoPreciptation-Sequencing (ChIP-Seq) analysis in a single Next generation DNA sequencing run. In th
e to-be-developed method: i) a set of… More
High-throughput screening and identification of scFv antibodies against glycosyla
Award Year / Program / Phase:
2010 / SBIR / Phase I
Agency:
HHS
Principal Investigator:
Margaret M. Kiss
Award Amount:
$193,520.00
Abstract:
DESCRIPTION (provided by applicant): The specific goal of this proposal is to develop a high-throughput method to identify scFv antibodies that recognize post-translationally modified proteins. We propose to complete a proof-of-concept for a new type of af
finity screening process based on emulsion,… More
A bifunctional antibody screening system for both phage display and yeast two-hyb
Award Year / Program / Phase:
2010 / SBIR / Phase I
Agency:
HHS
Principal Investigator:
Michael P. Weiner
Award Amount:
$200,035.00
Abstract:
DESCRIPTION (provided by applicant): This is a proposal to establish a proof-of-principle for a vector system to isolate high-affinty antibodies through selective rounds in both yeast and Escherichia coli. Antibodies have quickly become extremely useful as
therapeutic medicines to treat a… More