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Whispering Gallery Mode Resonator Biosensor for Bioterrorist and Biowarfare Agent Detection

Award Information
Agency: Department of Defense
Branch: Navy
Contract: N00014-03-M-0137
Agency Tracking Number: N022-0921
Amount: $70,000.00
Phase: Phase I
Program: SBIR
Solicitation Topic Code: N/A
Solicitation Number: N/A
Timeline
Solicitation Year: N/A
Award Year: 2003
Award Start Date (Proposal Award Date): N/A
Award End Date (Contract End Date): N/A
Small Business Information
P.O. Box 80010
Austin, TX 78708
United States
DUNS: 022552900
HUBZone Owned: No
Woman Owned: No
Socially and Economically Disadvantaged: No
Principal Investigator
 Joel Tabb
 Principal Scientist
 (607) 272-0002
 jtabb@agavebio.com
Business Contact
 Noe Salazar
Title: President
Phone: (512) 671-1369
Email: nsalazar@agavebio.com
Research Institution
N/A
Abstract

Agave BioSystems, in collaboration with Dr. Robert Boyd, of the Institute of Optics at the University of Rochester, proposes to develop an ultra sensitive and highly specific biosensor based on whispering gallery mode (WGM) resonator technology forbioterrorist and biowarfare agent detection. This novel biosensor would couple the specificity of antibody detection with the increased sensitivity of WGM resonator technology. Simulations have demonstrated that WGM resonator technology can provide atleast an order of magnitude greater sensitivity as compared to current detection mechanisms such as SPR. The signal generated by this system provides a straightforward intensity reading allowing for use with simple and inexpensive instrumentation. Themicrofabrication of this detection mechanism, coupled with microfluidic systems to be developed in the Phase II, will result in a disposable biochip that can be readily used in a small, compact and portable instrument. As a result of the successfulcompletion of both the Phase I and Phase II programs, Agave BioSystems will have established the core technology to produce highly specific and sensitive pathogen detection instrumentation based on Whispering Gallery Mode disk resonators. These trulyinnovative instruments will be small and inexpensive, combining advances in solid-state optics and microfabrication with classical microbiology. Significant commercial opportunities exist for the economical and accurate detection of biowarfare, food-borne,and environmental pathogens as well as in diagnostic markets such as medical, veterinary, agricultural and point-of-care.

* Information listed above is at the time of submission. *

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