Fiscal Year:
2005
Title:
Portable Cell Maintenance System
Agency / Branch:
DOD / ARMY
Contract:
W81XWH-04-C-0140
Award Amount:
$750,000.00
Abstract:
Cultured cell-based biosensors offer insight into the physiological action of the agent of interest, which is an advantage over other types of sensors. The development of cell-based biosensors that are field-portable would increase their utility in toxicology and environmental monitoring. One of the most significant issues hampering the development of field portable cell-based biosensors is the maintenance of optimal cultured cell environment under field conditions. In the Phase I work, Agave BioSystems and Cornell University successfully demonstrated proof of concept for a cell maintenance system (CMS) with integrated pH, osmolarity, CO2 and temperature sensors to support multiple vertebrate cells and cell types. In the Phase I CMS instrument demonstration, endothelial cells, fibroblast cells, and neuronal networks were supported for at least 3 days. In the proposed Phase II effort, a compact, portable and rugged prototype cell maintenance system will be developed and constructed with integrated monitoring and environmental control. The system will be designed to maintain a variety of cell types for more than 30 days.
Small Business Information at Submission:
Agave Biosystems, Inc.
P.O. Box 80010 Austin, TX 78708
EIN/Tax ID:
161551819
DUNS:
N/A
Number of Employees:
Woman-Owned:
No
Minority-Owned:
No
HUBZone-Owned:
No
Research Institution Information:
CORNELL UNIV.
123 Day Hall, Cornell Universi
Ithaca, NY 14854
Contact:
Linda Brainard
Contact Phone:
(607) 255-7123
RI Type:
Nonprofit college or university