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Inhibition of Biofilm Formation Using Novel Nanostructured Surfaces

Award Information

National Aeronautics and Space Administration
Award ID:
Program Year/Program:
2005 / STTR
Agency Tracking Number:
Solicitation Year:
Solicitation Topic Code:
Solicitation Number:
Small Business Information
Agave BioSystems, Inc.
401 E. State Street Suite 200 Ithaca, AK 14850-
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Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
Phase 1
Fiscal Year: 2005
Title: Inhibition of Biofilm Formation Using Novel Nanostructured Surfaces
Agency: NASA
Contract: NNJ05JC12C
Award Amount: $100,000.00


Biofilms are ubiquitous in the environment. Few surfaces resist biofilm formation, most promote it. Biofilm formation poses problems in water systems as they can clog pipes and pores, block filters, reduce heat transfer, and in general restrict flow. Their metabolic products can aid corrosion, even of stainless steel. In potable water systems, both their metabolic products and the bacteria or fungi themselves directly pose a health hazard. A space environment appears to be a particularly favorable one for biofilm formation. Cell cultures have shown far higher rates of growth in low-gravity environments. Space radiation seems to accelerate microbial growth and foster their mutation. Within a closed environment with many non-replaceable resources, prevention of biofilm formation is paramount. To meet this need, Agave BioSystems and the Universities Space Research Association, propose to develop carbon nanotubes (CNTs) and other nanostructures for the prevention of biofilm growth. In this Phase I, we propose to demonstrate that the use of nanostructured materials can prevent or inhibit growth of biofilms due to geometry effects and that they can also be functionalized with a biocide.

Principal Investigator:

Joel S. Tabb

Business Contact:

Noe Salazar
Business Official
Small Business Information at Submission:

Agave BioSystems, Inc.
PO Box 80010 Austin, TX 78708

EIN/Tax ID: 161551819
Number of Employees:
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
Research Institution Information:
Universities Space Research Association (HQ)
10211 Wincopin Circle, Suite 500
Columbia, MD 21044
Contact: Noe Salazar
Contact Phone: (512) 671-1369
RI Type: Nonprofit college or university