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Treatment of Sepsis with Talactoferrin

Award Information

Agency:
Department of Health and Human Services
Branch:
N/A
Award ID:
88640
Program Year/Program:
2008 / SBIR
Agency Tracking Number:
GM077816
Solicitation Year:
N/A
Solicitation Topic Code:
N/A
Solicitation Number:
N/A
Small Business Information
AGENNIX, INC.
AGENNIX, INC. 8 GREENWAY PLZ, STE 910 HOUSTON, TX 77046 0892
View profile »
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: Yes
 
Phase 2
Fiscal Year: 2008
Title: Treatment of Sepsis with Talactoferrin
Agency: HHS
Contract: 4R44GM077816-02
Award Amount: $2,462,044.00
 

Abstract:

DESCRIPTION (provided by applicant): Severe sepsis is a major cause of morbidity and mortality throughout the world. It is the leading cause of death in non-coronary intensive care units (ICUs) in the United States, with more than 750,000 cases occurring e very year. This means that in the United States, more than 500 patients die from severe sepsis every day, with 28% to 50% of the patients succumbing to the disease process at an average cost of 22,000 per patient. Successful development of TLF-based thera py for sepsis would satisfy a significant unmet medical need. Agennix has now established a manufacture of a pharmaceutical-grade talactoferrin, it has demonstrated its safety in clinical studies for various indications, and is now interacting with the FDA to obtain a go-ahead to initiate clinical Phase 3 studies in cancer. The development of talactoferrin is therefore at a stage that a demonstration of its clinical efficacy in sepsis would put the generation of a product to treat sepsis on a relatively eas y and straightforward path.

Principal Investigator:

Atul Varadhachary
7135521091
AVARADHACHARY@AGENNIX.COM

Business Contact:


msmith@agennix.com
Small Business Information at Submission:

AGENNIX, INC.
AGENNIX, INC. 8 GREENWAY PLZ, STE 910 HOUSTON, TX 77046

EIN/Tax ID: 954405779
DUNS: N/A
Number of Employees: N/A
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No