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Award Information

Agency:
Department of Health and Human Services
Branch:
N/A
Award ID:
96231
Program Year/Program:
2010 / SBIR
Agency Tracking Number:
N43CO201000085
Solicitation Year:
N/A
Solicitation Topic Code:
NCI
Solicitation Number:
N/A
Small Business Information
Omega Optics, Inc.
10306 Sausalito Dr Austin, TX 78759-6113
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Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
 
Phase 1
Fiscal Year: 2010
Title: Not Available
Agency: HHS
Contract: N43CO201000085
Award Amount: $200,000.00
 

Abstract:

This proposal aims at developing a compact label-free biomolecule microarray for personalized and specific  diagnostic assays of various cancers and allergies using two-dimensional photonic crystal microcavity  devices. Defect engineered photonic crystals, with sub-micron dimensions have already demonstrated high  sensitivity to trace volumes of analytes. While biosensing has been demonstrated in these devices with  single biomolecules, no previous effort has been made to extend device capability to microarrays.  Particularly, patterning of multiple biomolecules on a few micron scales has faced challenges of binding  exclusivity and binding specificity. Our device consists of an array of photonic crystal microcavity resonators  coupled to a single photonic crystal waveguide that give rise to minima in the photonic crystal waveguide  transmission spectrum at the resonance frequency of the microcavity. When a probe biomolecule binds  specifically to a target biomolecule, coated exclusively on the microcavity, shift in microcavity resonance  translates to corresponding shift in photonic crystal waveguide transmission minimum. The method  eliminates labeling for analyte identification. The impact of our novel and robust multi-analyte sensing  technique can reach much further than the field of biomolecular science and diagnostics alone. Our research  will lead to highly parallel detection of multiple diseases and thus a low-cost personalized diagnostic assay.

Principal Investigator:

Swapnajit Chakravarty
(512) 996-8833
Small Business Information at Submission:

OMEGA OPTICS, INC.
10435 BURNET RD, STE 108 AUSTIN, TX 78758-4450

EIN/Tax ID: 743016162
DUNS: N/A
Number of Employees: N/A
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No