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Medical Food Cocktail for Alzheimer's Disease

Award Information

Agency:
Department of Health and Human Services
Branch:
N/A
Award ID:
79725
Program Year/Program:
2006 / SBIR
Agency Tracking Number:
AT003025
Solicitation Year:
N/A
Solicitation Topic Code:
N/A
Solicitation Number:
N/A
Small Business Information
AKESO HEALTH SCIENCES, LLC
AKESO HEALTH SCIENCES, LLC 4607 LAKEVIEW CYN, #561 WESTLAKE VILLAGE, CA 91361 4028
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Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
 
Phase 1
Fiscal Year: 2006
Title: Medical Food Cocktail for Alzheimer's Disease
Agency: HHS
Contract: 1R43AT003025-01
Award Amount: $100,000.00
 

Abstract:

DESCRIPTION (provided by applicant): More than 4.5 million Americans currently suffer from Alzheimer's Disease, a progressive neurodegenerative disease characterized by loss of memory, changes in personality, agitation, disorientation, loss of coordination, and finally, total loss of day-to-day functioning. Alzheimer's is a staggeringly expensive disease, costing the American economy more than $83.9 billion annually. The Alzheimer's Association estimates that by 2050 between 11.3 million and 16 million Americans will be Alzheimer's victims and that the overall economic impact of the disease will increase four-fold. Much of the cost of Alzheimer's is born by Medicare and Medicaid. There is currently no treatment that halts the overall progression of the disease. As such, there is a great need for a significant breakthrough in Alzheimer's prevention and treatment. There is a growing consensus that Alzheimer's is a multifactorial disease and it is possible that a "cocktail" of medicines or ingredients may be needed to successfully delay its onset or progression. The overall goal of this Phase I SBIR proposal is to formulate and conduct initial feasibility tests of a medical food cocktail composed of standardized herbal extracts, vitamins, and minerals that are demonstrated in the basic science and clinical medical literature to impact the biochemical and pathophysiological processes involved in Alzheimer's Disease. The first Specific Aim will be to formulate and standardize the cocktail, which will include extracts of tumeric, green tea, black pepper and vitamins and other nutritive ingredients. Once formulated, the second Specific Aim will be to test the effects of the cocktail on biochemical markers and immunohistochemistry related to neurodegeneration in a novel transgenic mouse model of Alzheimer's Disease that was developed at the University of California-Irvine. Plans for Phase II of the project include more extensive pre-clinical testing of the cocktail in mice, as well as clinical studies on the effect of the cocktail on cognitive functioning and markers for Alzheimer's Disease processes in humans, at the early stages of the disease. If such a medical food cocktail proves feasible and cost effective for use as a complementary or alternative therapy for Alzheimer's Disease, the devastating economical and societal costs of Alzheimer's may be drastically reduced.

Principal Investigator:

Curt H. Hendrix
8183861826
CHENDRIX@SOCAL.RR.COM

Business Contact:


8183861026
Small Business Information at Submission:

AKESO HEALTH SCIENCES, LLC
AKESO HEALTH SCIENCES, LLC 4607 LAKEVIEW CYN, #561 WESTLAKE VILLAGE, CA 91361

EIN/Tax ID: 151052888
DUNS: N/A
Number of Employees: N/A
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No