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Product Formulation and Process Design for Commercial Production of Soluable…

Award Information

Agency:
Department of Agriculture
Branch:
N/A
Award ID:
67135
Program Year/Program:
2006 / SBIR
Agency Tracking Number:
2004-00347
Solicitation Year:
N/A
Solicitation Topic Code:
N/A
Solicitation Number:
N/A
Small Business Information
AKTIV-DRY
2100 Central Ave., Suite 109 Boulder, CO 80301-
View profile »
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
 
Phase 2
Fiscal Year: 2006
Title: Product Formulation and Process Design for Commercial Production of Soluable Phytosterols
Agency: USDA
Contract: 2006-33610-17273
Award Amount: $296,000.00
 

Abstract:

Commercially available products rich in phytosterol may now be used to cut serum low-density lipoprotein by as much as 14 percent. Unfortunately, phytosterols are poorly soluble and therefore present unique problems concerning their ability to suppress cholesterol absorption in the gut. This impediment often leads to sub-optimal dosing and poor performance of phytosterol compounds and restricts their use in nutraceuticals and functional food products. One promising approach to enhancing the dissolution rate of such compounds is to formulate them as micro- and nano-size particles. The purpose of this Phase II SBIR is to produce amorphous phytosterol powders with rates of dissolution in water and body fluids that significantly exceed what is currently available in the commercial market. We will also demonstrate the physical stability of the amorphous particles over an 18 month shelf life. Finally, the Phase II work will provide an engineering design and analysis for integrating a CAN-BD process with an existing system for manufacturing phytosterol powders on a commercial scale.

Principal Investigator:

Brian Quinn
3033503060
bquinn@aktiv-dry.com

Business Contact:

Brian Quinn
President
3033503060
bquinn@aktiv-dry.com
Small Business Information at Submission:

Aktiv-Dry, LLC
6060 Spine Road Boulder, CO 80301

EIN/Tax ID:
DUNS: N/A
Number of Employees: N/A
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No