Electrochemical Enzyme Immunoassay to Test Blood HBV
DESCRIPTION (provided by applicant):Millions of Americans are infected by the
hepatitis B virus (HBV)-many of whom have no reason to believe they are
infected. There is a need to track down America's millions of HBV victims-as
well as a corresponding need for innovative technology to test blood for HBV.
HBV is clearly a national medical priority.
The overall goal of this project is to further develop and then integrate core
sensor and enzyme immunoassay technologies into a novel technique for the rapid
and accurate measurement of HBV levels in blood. We are targeting diagnostic
(detection) applications as well as quantitative measurement needs (to monitor
viral levels and treatment efficacy). The feasibility of our approach was
clearly demonstrated during Phase I. The Phase II goal is to
demonstrate/validate/optimize the integration of a unique electrochemical
measurement method with proprietary electrochemical enzyme immunoassay
architecture to produce a new diagnostic/monitoring capability for "real time,"
cost-effective HBV assessment in an outpatient setting.
The product we envision is a disposable HBV test strip that can be read by an
inexpensive, small (hand-held) instrument. It would represent a key development
in medical diagnostics that would address major domestic and international
market needs for low-cost HBV screening and monitoring.
PROPOSED COMMERCIAL APPLICATION: NOT AVAILABLE
Small Business Information at Submission:
Principal Investigator:Robert W. Henkens
2810 MERIDIAN PKY, STE 152 DURHAM, NC 27713
Number of Employees: