USA flag logo/image

An Official Website of the United States Government

HYBRIDS

Award Information

Agency:
Department of Energy
Branch:
N/A
Award ID:
1181
Program Year/Program:
1984 / SBIR
Agency Tracking Number:
1181
Solicitation Year:
N/A
Solicitation Topic Code:
N/A
Solicitation Number:
N/A
Small Business Information
Radiation Monitoring Devices, Inc.
44 Hunt St. Watertown, MA 02472-4699
View profile »
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
 
Phase 1
Fiscal Year: 1984
Title: HYBRIDS
Agency: DOE
Contract: N/A
Award Amount: $50,000.00
 

Abstract:

THE PRODUCTION OF HYBRIDOMAS BY CELL FUSION IS AN INCREASINGLY IMPORTANT ASPECT OF BOTH MEDICAL RESEARCH AND CLINICAL PROTOCOLS. IN PARTICULAR, IT HAS THE POTENTIAL FOR PROVIDING SENSITIVE DIAGNOSTIC REAGENTS TO RADIATION INDUCED CELL DAMAGE. WE HAVE RECENTLY CONDUCTED PRELIMINARY RESEARCH ON A NEW APPROACH, THE ELECTRONIC CELL FUSION TECHNIQUE. THIS TECHNIQUE USES AN ELECTRONIC IMPULSE TO PUNCTURE THE MEMBRANE AT THE POINT OF CELL CONTACT WHICH IMMEDIATELY INDUCES THE ONSET OF FUSION. THIS METHOD HAS THE POTENTIAL TO MAKE POSSIBLE THE SUCCESSFUL FUSION OF A WIDE VARIETY OF CELL PARTNERS NOT PREVIOUSLY ADDRESSABLE. RMD, INC. IN COLLABORATION WITH THE MASSACHUSETTS GENERAL HOSPITAL PROPOSES TO DO THE RESEARCH NECESSARY TO DEVELOP A RELIABLE AND PRACTICAL TECHNIQUE FOR PRODUCING AN ANTIBODY DIAGNOSTIC ASSAY TECHNIQUE FOR QUANTIFYING RADIATION INDUCED DAMAGE. IN PHASE I WE WILL FOCUS ON RESEARCH TO DEMONSTRATE BOTH THE POTENTIAL STRENGTHS OF THE ELECTRONIC CELL FUSION TECHNIQUE WITH RESPECT TO HUMAN T-CELLS. IN PHASE II, WE WILL PERFECT THE TECHNIQUE AND FIRST MAKE THE REQUIRED SPECIFIC ANTI T-CELL ANTIBODIES.

Principal Investigator:

Gerald entine, ph.d.
PRESIDENT
0

Business Contact:

Small Business Information at Submission:

Radiation Monitoring Devices
44 Hunt Street Watertown, MA 02172

EIN/Tax ID:
DUNS: N/A
Number of Employees: N/A
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No