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HIGH PERFORMANCE DETECTOR FOR SMALL ANIMAL PET

Award Information

Agency:
Department of Health and Human Services
Branch:
N/A
Award ID:
60146
Program Year/Program:
2002 / SBIR
Agency Tracking Number:
RR015992
Solicitation Year:
N/A
Solicitation Topic Code:
N/A
Solicitation Number:
N/A
Small Business Information
Radiation Monitoring Devices, Inc.
44 Hunt Street Watertown, MA 02472-4699
View profile »
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
 
Phase 2
Fiscal Year: 2002
Title: HIGH PERFORMANCE DETECTOR FOR SMALL ANIMAL PET
Agency: HHS
Contract: 2R44RR015992-02
Award Amount: $750,000.00
 

Abstract:

DESCRIPTION (provided by applicant):Positron Emission Tomography (PET) is an in vivo analog of autoradiography, which makes it a potentially powerful new tool for imaging biological processes and molecular targets in small laboratory animals. Its fundamental advantage is that functional data can be obtained non-invasively, allowing each animal to be studied repeatedly. Thus, each animal can serve as its own control in studies with a longitudinal design. There is significant interest in small animal PET within the pharmaceutical and biotechnology industry because in vivo quantification of biological processes to measure an agent'smechanism of action and its concentration at the site of action are of great importance in drug development. While the advantages of small animal imaging with PET are obvious, the challenges are also very significant. The main barriers to using PET in studies of laboratory animals have traditionally been poor spatial resolution, low sensitivity, and high cost. To address these deficiencies, we propose to develop a detector that can achieve extremely fine spatial resolution and high sensitivity in a cost-effective manner. The detector will be based on finely pixelated monolithic block of scintillator coupled to a position sensitive detector. Phase II efforts will focus on the development of a proof-of-concept benchtop small-animal PET system, consisting of a small number of complete detector modules.

Principal Investigator:

Vivek V. Nagarkar
6179261167
VNAGARKAR@RMDINC.COM

Business Contact:

Gerald Entine
6179261167
GENTINE@RMDINC.COM
Small Business Information at Submission:

RADIATION MONITORING DEVICES, INC.
RADIATION MONITORING DEVICES INC 44 HUNT ST WATERTOWN, MA 02472

EIN/Tax ID: 042546395
DUNS: N/A
Number of Employees: N/A
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No