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BANDWIDTH-SELECTIVE, MLA APD-BASED FLOW CYTOMETER

Award Information
Agency: Department of Health and Human Services
Branch: National Institutes of Health
Contract: 1R43RR017126-01
Agency Tracking Number: RR017126
Amount: $99,902.00
Phase: Phase I
Program: SBIR
Solicitation Topic Code: N/A
Solicitation Number: N/A
Timeline
Solicitation Year: N/A
Award Year: 2002
Award Start Date (Proposal Award Date): N/A
Award End Date (Contract End Date): N/A
Small Business Information
RADIATION MONITORING DEVICES INC 44 HUNT ST
WATERTOWN, MA 02472
United States
DUNS: N/A
HUBZone Owned: No
Woman Owned: No
Socially and Economically Disadvantaged: No
Principal Investigator
 MITCHELL WOODRING
 (617) 926-1167
 MWOODRING@RMDINC.COM
Business Contact
 GERALD ENTINE
Phone: (617) 926-1167
Email: GENTINE@RMDINC.COM
Research Institution
N/A
Abstract

In this Phase I work, we propose to carry out the research necessary to develop, test, and characterize a sophisticated, by avalanche-photodiode (APD) arrangement as a compact, high-performance replacement for photomultiplier tubes used in flow cytomers. Development of a high- performance, monolithic, linear array (MLA) of avalanche photodiodes is the Phase I focus. Successful testing and characterization of this novel photodetector, as proposed here, will buttress the larger research plan to develop a sophisticated flow cytomer utilizing several exciting new technologies to dramatically increase flow cytometer performance and utility. It is anticipated that in advanced research the final envisioned devise will have multiple lasers, sophisticated focusing optics, MLA-APD photodetectors, and a compact, high performance readout system. This advanced development will result in a flow cytometer are not currently used with good efficacy. Exciting new flow-cytometry applications ranging from monitoring municipal water supplies for pathogens to agricultural applications for live stock health management will then be possible. PROPOSED COMMERCIAL APPLICATIONS: Commercially, flow cytometers have wide market acceptance for use a score diagnostic devices in pathology and immunology departments in many hospitals across the United States. Since the market is established for these devices, our high-performance, extremely compact device should find broad acceptance and provide immediate technological improvement in the diagnosis and science carried out with flow cytometers.

* Information listed above is at the time of submission. *

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