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SPECT/CT IMAGING OF SMALL ANIMALS

Award Information

Agency:
Department of Health and Human Services
Branch:
N/A
Award ID:
59824
Program Year/Program:
2002 / SBIR
Agency Tracking Number:
CA094379
Solicitation Year:
N/A
Solicitation Topic Code:
N/A
Solicitation Number:
N/A
Small Business Information
Radiation Monitoring Devices, Inc.
44 Hunt St. Watertown, MA 02472-4699
View profile »
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
 
Phase 1
Fiscal Year: 2002
Title: SPECT/CT IMAGING OF SMALL ANIMALS
Agency: HHS
Contract: 1R43CA094379-01
Award Amount: $505,497.00
 

Abstract:

DESCRIPTION (provided by applicant): Nuclear medicine techniques (such as SPECT) have the potential to become powerful new tool in imaging biological processes in small laboratory animals. With the ever increasing number of human disease models, particularly in the smaller animals such as mice and rats [Bernstein, Doetschman, Hanahan], the potential of high resolution nuclear medicine technology to contribute unique information is becoming apparent to many researchers. The critical advantage of nuclear medicine procedures is that they allow functional information to be obtained non-invasively, so each animal can be studied repeatedly. It needs to be pointed out that the obvious advantages of SPECT are accompanied by some limitations. Most importantly, SPECT images do not provide detailed anatomical information needed for localization studies. Additionally, the non uniform attenuation of gamma rays by the surrounding tissue causes image distortions and quantitative errors in reconstructed SPECT and PET images. These limitations in SPECT imaging can be overcome by combining SPECT imaging with X-ray CT imaging. The goal of the proposed effort is investigate two high resolution detector systems to allow combined SPECT/CT imaging of small animals.

Principal Investigator:

Michael R. Squillante
6179261167
MSQUILLANTE@RMDINC.COM

Business Contact:

Gerald Entine
6179261167
GENTINE@RMDINC.COM
Small Business Information at Submission:

RADIATION MONITORING DEVICES, INC.
RADIATION MONITORING DEVICES INC 44 HUNT ST WATERTOWN, MA 02472

EIN/Tax ID: 042546395
DUNS: N/A
Number of Employees: N/A
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No