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A Dual Modality Imaging System for Small Animal Imaging

Award Information

Agency:
Department of Energy
Branch:
N/A
Award ID:
80477
Program Year/Program:
2006 / SBIR
Agency Tracking Number:
80496S06-I
Solicitation Year:
N/A
Solicitation Topic Code:
N/A
Solicitation Number:
N/A
Small Business Information
Radiation Monitoring Devices, Inc.
44 Hunt Street Watertown, MA 02472-4699
View profile »
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
 
Phase 1
Fiscal Year: 2006
Title: A Dual Modality Imaging System for Small Animal Imaging
Agency: DOE
Contract: DE-FG02-06ER84432
Award Amount: $100,000.00
 

Abstract:

The ideal biological imaging system would provide non-invasive, high-resolution, high-sensitivity three-dimensional (3D) images of living systems. Positron Emission Tomography (PET) offers high sensitivity to a range of biological processes through the use of targeted radiolabeled probes. Unfortunately, precise signal localization can be extremely difficult, due to low spatial resolution and the lack of anatomical information. Magnetic Resonance Imaging (MRI) can provide high spatial resolution and excellent soft tissue contrast, but MRI suffers from poor signal strength, leading to low sensitivity. Because these single modalities do not satisfy all requirements, this project will combine the best features of PET and MR modalities into a single imaging instrument for small animal studies. The instrument will record data in both imaging modalities nearly simultaneously. Phase I will demonstrate the feasibility of the imaging system by designing and building PET detector modules that can be operated inside a small-animal MR scanner. The effect of the PET and MR detectors on each other will be analyzed. Commercial Applications and Other Benefits as described by the Applicant: Over and above the use in nuclear medicine, the proposed gamma-ray technology should find use in nuclear and particle physics, space research, homeland security, environmental monitoring, and synchrotron studies.

Principal Investigator:

Gerald Entine
Dr.
6176686800
GEntine@rmdinc.com

Business Contact:

Gerald Entine
Dr.
6176686800
GEntine@rmdinc.com
Small Business Information at Submission:

Radiation Monitoring Devices, Inc.
44 Hunt Street Watertown, MA 02472

EIN/Tax ID:
DUNS: N/A
Number of Employees:
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No