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New Solid-State Photosensor for PET

Award Information

Department of Health and Human Services
Award ID:
Program Year/Program:
2009 / SBIR
Agency Tracking Number:
Solicitation Year:
Solicitation Topic Code:
Solicitation Number:
Small Business Information
Radiation Monitoring Devices, Inc
44 Hunt Street Watertown, MA 02472-4699
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Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
Phase 2
Fiscal Year: 2009
Title: New Solid-State Photosensor for PET
Agency: HHS
Contract: 2R44NS060197-02
Award Amount: $1,285,160.00


DESCRIPTION (provided by applicant): New, Solid-State Photosensor for PET Positron Emission Tomography (PET) is a functional imaging technique with potential to quantify the rates of biological processes in vivo. The availability of short lived positron-em itting isotopes of carbon, nitrogen, oxygen and especially fluorine, allows virtually any compound of biological interest to be labeled in trace amounts and introduced into the body for imaging with PET. The distribution of the tracer is imaged dynamically , allowing the rates of biological processes to be calculated using appropriate mathematical models. PET imaging can provide diagnosis for symptoms of diseases such as Alzheimer's disease, head trauma, and stroke. PET technology is also playing a prominent and an increasingly visible role in modern cancer research, clinical diagnosis and oncology. While PET is a powerful imaging tool, the performance of current clinical PET systems is limited by the available detector technology, and there is an urgent need for improvement in PET instrumentation, in order to exploit the full potential of this promising technique. The goal of the proposed effort is to design, build and implement new, solid-state photodetectors for reading out scintillation crystals in PET ima ging. High energy, timing, spatial, depth-of-interaction resolution, as well as high efficiency, can be expected with the PET modules based on the proposed photodetectors. PUBLIC HEALTH RELEVANCE: New, Solid-State Photosensor for PET The goal of the propos ed research is to investigate and implement novel photodetectors for next generation medical imaging systems. These photodetectors are also very promising for homeland security, nuclear physics research, health physics instrumentation, non-destructive eval uation and materials science studies.

Principal Investigator:

Gerald Entine

Business Contact:

Nancy Marshall
Small Business Information at Submission:

44 Hunt Street WATERTOWN, MA 02472

EIN/Tax ID: 042546395
Number of Employees: N/A
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No