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Company Information:

Company Name:
ALLELE BIOTECHNOLOGY AND PHARMACEUTICALS
Address:
9924 Mesa Rim Road
SAN DIEGO, CA 92121-2910
Phone:
N/A
URL:
N/A
EIN:
152220107
DUNS:
021345447
Number of Employees:
N/A
Woman-Owned?:
No
Minority-Owned?:
Yes
HUBZone-Owned?:
No

Award Totals:

Program/Phase Award Amount ($) Number of Awards
SBIR Phase I $1,575,475.00 10

Award List:

EFFICIENT CELL-FREE SELECTION OF ANTIBODIES

Award Year / Program / Phase:
2001 / SBIR / Phase I
Award Amount:
$99,700.00
Agency:
HHS
Principal Investigator:
Jiwu Wang
Abstract:
DESCRIPTION: The objective of this proposal is to develop a novel cell-free system that would facilitate rapid selection of functional fragments of monoclonal antibodies. The system descibed is based on well-established molecular mechanisms. For antibody selection, a cDNA… More

Novel Technology for Field Detection of Gene Expression

Award Year / Program / Phase:
2001 / SBIR / Phase I
Award Amount:
$199,341.00
Agency:
HHS
Principal Investigator:
Jiwu Wang
Abstract:
DESCRIPTION (provided by applicant): The general aim of this proposal is to develop and commercialize an innovative technology for gene expression profiling. This proprietary technology is based on direct amplification of RNA by RNA… More

Innovative RNA Profiling in Cancer Cells

Award Year / Program / Phase:
2001 / SBIR / Phase I
Award Amount:
$149,500.00
Agency:
HHS
Principal Investigator:
Jiwu Wang
Abstract:
The ultimate goal of this proposal is to develop and commercialize a novel and powerful assay system for amplification and detection of gene transcripts in cancer-related studies. Specifically, our proprietary technology is targeted to providing tools for two types of applications. First, we will… More

Cell Microarrays for High Throughput RNAi

Award Year / Program / Phase:
2003 / SBIR / Phase I
Award Amount:
$99,510.00
Agency:
HHS
Principal Investigator:
Abstract:
DESCRIPTION (provided by applicant): The goal of this proposal is to further develop and adapt our existing DNA-based RNAi technology to a cell microarray format for high throughput gene function studies and potential drug screening efforts. The principle of arrays of living cells for "reverse… More

Advanced Platform of RNAi Technology

Award Year / Program / Phase:
2003 / SBIR / Phase I
Award Amount:
$99,510.00
Agency:
HHS
Principal Investigator:
Abstract:
RNA interference (RNAi) is a powerful tool for gene function studies and drug development. Currently, application of this technology is largely limited by the efficiency of delivering RNAi-inducing reagents into mammalian cells. The aim of this proposal is to establish techniques to efficiently… More

SBIR PHASE I, TOPIC 239 YEAST SINGLE CHAIN ANTIBODIES AS CAPTURE REAGENTS

Award Year / Program / Phase:
2007 / SBIR / Phase I
Award Amount:
$150,000.00
Agency:
HHS
Principal Investigator:
Wang Jiwu
Abstract:
N/a

RNA Resource for Synthetic Lethal Screening of DNA Repair and

Award Year / Program / Phase:
2010 / SBIR / Phase I
Award Amount:
$199,918.00
Agency:
HHS
Principal Investigator:
Jiwu Wang
Abstract:
The objectives of this proposal are to develop gene silencing reagents, and to test/validate their use in  synthetic lethal screening of DNA damage signaling and repair pathways. Making such reagents available will provide the efficiency and convenience that cancer researchers currently need to… More

Improving Pediatric Developmental Screening and Communication: A CME

Award Year / Program / Phase:
2013 / SBIR / Phase I
Award Amount:
$199,939.00
Agency:
HHS
Principal Investigator:
Jiwu Wang – 858-587-6645
Abstract:
DESCRIPTION (provided by applicant): The goal of the proposed project is to develop a commercial kit that will allow drug addiction researchers with ongoing projects using cell-based models to be able to successfully and conveniently produce human inducedpluripotent stem cells (iPSCs). Addiction to… More

Nano-Antibodies for Studying RNA Modifications

Award Year / Program / Phase:
2014 / SBIR / Phase I
Award Amount:
$225,000.00
Agency:
HHS
Principal Investigator:
Jiwu Wang – 858-587-6645
Abstract:
DESCRIPTION (provided by applicant): The goal of the proposed Phase I research is to develop a set of commercial reagents for recognizing 2'-O-methyladenosine (Am), 2'-O-methylcytidine (Cm), 2'-O-methylguanosine (Gm) or 2'-O-methyluridine (Um), as well asindiscriminately to all… More

RNA-Guided Gene Targeting in Human Cells

Award Year / Program / Phase:
2014 / SBIR / Phase I
Award Amount:
$153,057.00
Agency:
HHS
Principal Investigator:
Jiwu Wang – 858-587-6645
Abstract:
Project Summary/Abstract The goal of the proposed Phase I research is to develop a set of commercial kits for footprint-free genome engineering. The core technologies that serve as the foundation of these kits are based on the CRISPR/cas system, which wasoriginally identified in bacteria and… More