SBIR Phase I: Aerosolized Biological Agents Detection
This Small Business Innovation Research (SBIR) Phase I project will develop a fast, reliable and sensitive technology that can identify the nature and the content of the particles in aerosol samples, and provide an early warning of the presence of bio-warfare agents. Current biological agent detection systems rely on point detectors that cannot sample actual aerosol condition in real-time. Additionally, standoff detectors are large, expensive and not suitable for use in urban terrain. With a unique combination of bio-identification and ultra-sensitivity particle counting, the proposed project will develop an extremely sensitive, yet reliable detection and monitoring system that can satisfy most current and potential needs for bio-agents detection. This Phase I project has two specific aims: (1) to determine the optimal conditions for the detection of bacterial spores (eg. Bacillus subtilis) with highest sensitivity using antibodies; and (2) to demonstrate that the retained bacterial spores can be detected by a particle counter operated in solution at a sensitivity sufficient to detect few hundred particles. A testing device will be designed and produced based on these results at the end of the project.
The commercial application of this project is in the area of homeland security.
Small Business Information at Submission:
Principal Investigator:Sitong Sheng
P.O.Box 3423 Charlottesville, VA 22903
Number of Employees: