DESCRIPTION (provided by applicant): The pace at which the genetics of cancer is being deciphered has been accelerating. Researchers have begun to characterize in detail multiple genetic mechanisms that give rise to cancer, as well as numerous functional pathways associated with cancer, such as… More

DESCRIPTION (provided by applicant) In the area of cancer, microarray analysis is being used to identify specific differences between normal and disease tissues. Such efforts are leading to the identification of small gene sets, or signatures, that can provide key information for classifying… More

DESCRIPTION (provided by applicant): The overall goal of this proposal is to provide a pathway for translating microarray-based research in cancer and toxicology into cost efficient, high throughput, validated assays for the assessment of a range of different toxicological and oncological… More

DESCRIPTION (provided by applicant): Proposed here is the development and application of a high-throughput, multiplexed PCR-based approach to gene expression analysis to broadly enable the use of gene expression profiling for drug research, development and high content screening. The proposed… More