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Validating and Translating Array Signatures
- Small Business Information
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Woman-Owned: NoMinority-Owned: NoHUBZone-Owned: No
- Phase 1
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Fiscal Year: 2004Title: Validating and Translating Array SignaturesAgency: HHSContract: 1R43CA110542-01Award Amount: $99,999.00
Abstract:
DESCRIPTION (provided by applicant) In the area of cancer, microarray analysis is being used to identify specific differences between normal and disease tissues. Such efforts are leading to the identification of small gene sets, or signatures, that can provide key information for classifying cancer types. We propose here a mechanism for translating these discoveries into cost-effective, quantitative assays based on the use of highly multiplexed, universal-primer-driven rtPCR (UP-rtPCR). In this proposal we will demonstrate and validate the combined use of artificial neural network analysis for identification of small gene signatures and UP-rtPCR technology for translating these signatures into high throughput assays for use in research and clinical settings. Success will be measured by the ability of this approach to differentiate 4 types of small, round, blue-cell tumors. This work will be performed in collaboration with Drs. Javed Khan and Gary Fogel.Small Business Information at Submission:Business Contact:
8588820130ALTHEA TECHNOLOGIES, INC.
ALTHEA TECHNOLOGIES, INC. 11040 ROSELLE ST SAN DIEGO, CA 92121EIN/Tax ID: 330788907DUNS: N/ANumber of Employees: N/AWoman-Owned: NoMinority-Owned: NoHUBZone-Owned: No
Award Information
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Agency: Department of Health and Human Services |
Branch: N/A |
Award ID: 70733 |
Program Year/Program: 2004 / SBIR |
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Agency Tracking Number: CA110542 |
Solicitation Year: N/A |
Solicitation Topic Code: N/A |
Solicitation Number: N/A |