USA flag logo/image

An Official Website of the United States Government

Self-Organizing Biomolecular Materials as Structural and Patterning Elements…

Award Information

Agency:
Department of Defense
Branch:
Army
Award ID:
28743
Program Year/Program:
1996 / SBIR
Agency Tracking Number:
28743
Solicitation Year:
N/A
Solicitation Topic Code:
N/A
Solicitation Number:
N/A
Small Business Information
AMBERGEN, INC
AMBERGEN, INC 313 PLEASANT ST WATERTOWN, MA -
View profile »
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
 
Phase 2
Fiscal Year: 1996
Title: Self-Organizing Biomolecular Materials as Structural and Patterning Elements for Device Fabrication
Agency / Branch: DOD / ARMY
Contract: N/A
Award Amount: $599,093.00
 

Abstract:

The engineering of materials on a nanometer scale is an important technological goal which would facilitate the development of a new generation of materials and devices. A variety of biological membranes exhibit self-assembly into 2-D arrays including the purple membrane from Halobacteria salinarium and the S-layer from Sulfolobus acidocaldarius. Methods have been developed to use these membranes as patterning elements and templates for device fabrication. In addition, conditions have been found where self-assembled membranes are stable up to 140 degrees Celsius. In Phase I AmberGen, Inc. will evaluate several new methods for characterizing and controlling self-assembly in these systems. These methods include: i) genetic engineering and in vitro production of self-assembling proteins with novel features for device fabrication; ii) site-specific incorporation of special linker molecules into proteins for the regulation of self-assembly, attachment to device substrates, co-crystallization of other biologically active proteins and patterning within a self-assembled array; iii) attenuated total reflection-Fourier transform infrared (ATR-FTIR) spectroscopy for investigating the link between biomolecular structure and macroscopic self-assembly.

Principal Investigator:

Dr. Parshuram Rath
6172449324

Business Contact:

Small Business Information at Submission:

Ambergen, Inc.
97 Dorcar Rd Newton, MA 02159

EIN/Tax ID:
DUNS: N/A
Number of Employees:
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No