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Microarray Assay for Detection of Lab Animal Pathogens

Award Information

Agency:
Department of Health and Human Services
Branch:
N/A
Award ID:
71242
Program Year/Program:
2004 / SBIR
Agency Tracking Number:
AI060215
Solicitation Year:
N/A
Solicitation Topic Code:
N/A
Solicitation Number:
N/A
Small Business Information
AMBERGEN, INC
AMBERGEN, INC 313 PLEASANT ST WATERTOWN, MA -
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Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
 
Phase 1
Fiscal Year: 2004
Title: Microarray Assay for Detection of Lab Animal Pathogens
Agency: HHS
Contract: 1R43AI060215-01
Award Amount: $121,713.00
 

Abstract:

DESCRIPTION (provided by applicant): The main goal of this project is to develop a microarray based system for comprehensive health assessment of laboratory animals. This microarray based test would be capable of simultaneous testing for the presence of all relevant pathogens and would require only a small amount of blood or serum. During Phase I, AmberGen in collaboration with Pulsar Clinical Technologies Inc., a subcontractor on this project, plans to develop and evaluate critical components of a microarray assay system for the detection of multiple pathogen-specific antibodies circulating in blood of laboratory animals. This integrated system will be based on a proprietary microarray technology fabrication method utilizing nitrocellulose suspension. This method results in microarray substrates with high binding capacity and low background fluorescence. During Phase I several critical components of this assay system will be evaluated, including antigen binding capacity, sensitivity, specificity and reproducibility using several model antigens derived from mouse pathogens and mouse sera of known status. During Phase II a microarray assay capable of testing for all relevant pathogens in mice will be developed for animal facilities use. Dr. Nirah Shomer, Associate Director of Boston University Animal Science center will serve as a consultant on this project.

Principal Investigator:

Jerzy Olejnik
6179750685
JERZY@AMBERGEN.COM

Business Contact:

Norman Priebatsch
6179750688
NEP@AMBERGEN.COM
Small Business Information at Submission:

AMBERGEN, INC.
AMBERGEN, INC. 1106 COMMONWEALTH AVE BOSTON, MA 02215

EIN/Tax ID: 043228005
DUNS: N/A
Number of Employees: N/A
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No